Cynomolgus HGFA Protein (pro form)

Recombinant Cynomolgus HGFA Protein (pro form) is expressed from HEK293 with His tag at the C-Terminus.It contains Gln34-Ser650. Hepatocyte growth factor activator (HGFA) is a serine protease initially identified as a potent activator of hepatocyte growth factor/scatter factor. Hepatocyte growth factor/scatter factor is known to be critically involved in tissue morphogenesis, regeneration, and tumor progression, via its receptor, MET.In vivo, HGFA also activates macrophage-stimulating protein, which has roles in macrophage recruitment and inflammatory processes, cellular survival and wound healing through its receptor, RON.