Cyclophilin D, Recombinant, Human (PPID, Peptidylprolyl Isomerase D, 40kD Peptidyl-Prolyl cis-trans

Cyclophilin D, Recombinant, Human (PPID, Peptidylprolyl Isomerase D, 40kD Peptidyl-Prolyl cis-trans
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
C8855-21.100 100 µg - -

3 - 19 Werktage*

644,00 €
 
Cyclophilin D (also known as peptidylpropyl isomerase D, PPID) is a member of peptidyl-propyl... mehr
Produktinformationen "Cyclophilin D, Recombinant, Human (PPID, Peptidylprolyl Isomerase D, 40kD Peptidyl-Prolyl cis-trans"
Cyclophilin D (also known as peptidylpropyl isomerase D, PPID) is a member of peptidyl-propyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. This protein can bind to the immunosuppressant cyclosporine A and was known that its overexpression suppresses the apoptosis in cancer cells. Recombinant human cyclophilin D was expressed in E.coli and purified by conventional chromatography techniques. Molecular Weight: 42.9kD (390 aa), Sequences: MGSSHHHHHH SSGLVPRGSH MSHPSPQAKP SNPSNPRVFF DVDIGGERVG RIVLELFADI VPKTAENFRA LCTGEKGIGH TTGKPLHFKG CPFHRIIKKF MIQGGDFSNQ NGTGGESIYG EKFEDENFHY KHDREGLLSM ANAGRNTNGS QFFITTVPTP HLDGKHVVFG QVIKGIGVAR ILENVEVKGE KPAKLCVIAE CGELKEGDDG GIFPKDGSGD SHPDFPEDAD IDLKDVDKIL , LITEDLKNIG NTFFKSQNWE MAIKKYAEVL RYVDSSKAVI ETADRAKLQP IALSCVLNIG ACKLKMSNWQ GAIDSCLEAL ELDPSNTKAL YRRAQGWQGL KEYDQALADL KKAQGIAPED KAIQAELLKV KQKIKAQKDK EKAVYAKMFA, Enzyme Activity: Specific activity is > 700 nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAFP-PNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin. Applications: , Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Schlagworte: PPIase D, EC=5.2.1.8, Rotamase D, Cyclophilin-related protein, Peptidyl-prolyl cis-trans isomerase D, 40 kDa peptidyl-prolyl cis-trans isomerase
Hersteller: United States Biological
Hersteller-Nr: C8855-21

Eigenschaften

Anwendung: WB
Konjugat: No
Spezies-Reaktivität: human
Format: Highly Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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