CTHRC1 (mouse) (rec.)

Mouse CTHRC1 (aa 33-245) is fused at the N-terminus to a FLAG(R)-tag. Collagen Triple Helix Repeat Containing-1 (CTHRC1) is a 30kDa glycosylated secretory protein containing a short collagen-like motif contributing to vascular remodeling by limiting collagen matrix deposition and promoting cell migration. CTHRC1 is expressed in calcified atherosclerotic plaque and chondrocyte-like cells. Aberrant expression of CTHRC1 is present in human solid cancers and likely to be associated with cancer invasion and metastasis.