Cryptic Protein Protein(C-6His) (recombinant human)

Protein Construction: Recombinant Human Cryptic protein is produced by our Mammalian expression system and the target gene encoding Tyr26-Gly169 is expressed with a 6His tag at the C-terminus. Sequence: Tyr26-Gly169. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 20 kDa. Protein function: Cryptic (CFC1) is a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family. It contains an EGF-like domain, and is glycosylated on its N-terminal during post-translational modification. Cryptic is identified as a NODAL coreceptor involved in the correct establishment of the left-right axis. It may play a role in mesoderm and/or neural patterning during gastrulation. The unnormal expression of this gene may causes a series of diseases such as HTX2, Transposition of the great arteries dextro-looped 2, and Conotruncal heart malformations. Protein function: NODAL coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation. [The UniProt Consortium]