Canine HE4 Protein

Recombinant Canine HE4 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gly28-Phe124. The ovarian cancer biomarker HE4 is known to promote proliferation, metastasis, chemoresistance, and suppression of cytotoxic lymphocytes. HE4 has the ability to affect signaling events and gene expression in multiple cell types of the tumor microenvironment, which could contribute to angiogenesis and altered immunogenic responses in ovarian cancer.