ZFPM2 (Vector pUC, Accession No. BC109222)

Length: 3456 Sequence: ATGTCCCGGC GAAAGCAAAG CAAACCCCGG CAGATCAAAC GGCCGCTTGA AGATGCCATT GAAGATGAGG AAGAAGAATG TCCATCAGAG GAAACAGACA TCATCTCCAA AGGAGACTTT CCATTGGAGG AAAGCTTTTC CACAGAATTT GGGCCTGAAA ATCTGAGCTG CGAAGAAGTG GAATACTTTT GTAACAAAGG TGATGATGAA GGAATCCAGG AGACAGCAGA ATCAGATGGG GACACACAGT CAGAGAAACC GGGGCAACCT GGAGTTGAGA CAGACGACTG GGATGGACCA GGAGAGCTGG AGGTGTTTCA GAAAGATGGG GAACGAAAAA TTCAGAGTCG ACAGCAACTT CCAGTGGGAA CAACCTGGGG GCCGTTTCCT GGGAAGATGG ACTTGAATAA TAATTCTTTG AAGACAAAGG CTCAGGTCCC AATGGTGCTG ACTGCTGGTC CCAAGTGGTT GCTGGATGTG ACTTGGCAAG GAGTGGAAGA CAACAAAAAC AACTGCATTG TGTACAGCAA AGGGGGTCAG CTTTGGTGTA CAACTACGAA GGCCATCTCT GAGGGTGAAG AGCTAATTGC CTTTGTGGTG GATTTTGACT CAAGGCTACA AGCTGCCAGT CAGATGACTC TCACAGAAGG GATGTACCCT GCACGCCTGC TGGACTCAAT TCAGCTGCTT CCTCAGCAAG CTGCCATGGC TTCTATTTTG CCCACAGCTA TTGTCAATAA GGATATATTC CCTTGCAAGT CCTGTGGCAT CTGGTATCGG AGTGAGCGGA ATCTGCAGGC CCATTTGATG TACTACTGCA GTGGGAGGCA AAGAGAAGCT GCTCCGGTGT CAGAGGAAAA TGAAGACAGT GCCCATCAGA TTTCCAGCCT GTGCCCCTTC CCACAGTGCA CCAAGAGCTT TTCAAATGCT CGAGCTCTAG AAATGCACCT GAATTCACAC AGTGGAGTGA AAATGGAAGA ATTCCTGCCC CCTGGTGCTA GTCTAAAATG CACCGTCTGT AGCTACACTG CTGATTCCGT GATCAACTTT CACCAACACC TGTTCTCCCA TCTCACTCAA GCTGCCTTCC GATGTAATCA CTGCCATTTC GGCTTCCAGA CTCAGAGGGA GTTATTGCAG CACCAGGAGC TCCATGTCCC TAGCGGCAAA CTTCCCAGAG AAAGTGACAT GGAACACTCT CCAAGTGCAA CTGAAGACAG CTTACAGCCA GCCACAGACT TATTGACCAG AAGCGAACTT CCCCAGAGCC AAAAGGCCAT GCAGACTAAA GATGCGAGCT CTGACACAGA GCTGGACAAG TGTGAGAAAA AGACTCAGCT CTTTCTCACG AACCAGAGAC CAGAGATACA GCCTACAACA AATAAACAAA GCTTTTCTTA CACAAAAATA AAGTCTGAGC CCTCTAGCCC AAGACTTGCC TCATCTCCAG TTCAGCCTAA TATTGGGCCT TCTTTCCCTG TGGGCCCTTT CCTATCTCAG TTTTCTTTCC CCCAAGATAT CACCATGGTC CCTCAAGCTT CAGAGATCTT AGCTAAGATG TCTGAACTGG TGCATCGGCG ACTGAGGCAT GGCAGTAGTA GCTACCCTCC CGTCATTTAC AGCCCTTTGA TGCCCAAGGG GGCTACTTGT TTTGAGTGTA ACATAACATT CAATAATTTG GATAATTATC TAGTGCACAA AAAGCATTAT TGCAGCAGCC GATGGCAGCA GATGGCTAAG TCCCCAGAGT TCCCTAGTGT GTCAGAAAAG ATGCCTGAAG CTTTGAGTCC CAACACTGGC CAAACCTCCA TAAACCTTCT CAACCCAGCT GCTCATTCTG CTGATCCTGA GAATCCACTT CTTCAAACAT CTTGCATCAA TTCTTCCACT GTCTTAGATT TAATTGGGCC AAATGGGAAG GGCCATGACA AGGACTTTTC CACTCAAACT AAGAAGCTCT CCACCTCCAG TAACAATGAT GACAAAATTA ATGGAAAACC TGTTGATGTG AAAAATCCCA GTGTCCCCTT AGTGGATGGG GAAAGTGACC CAAATAAGAC TACCTGTGAA GCTTGCAACA TTACCTTCAG CCGGCACGAA ACATACATGG TCCACAAACA GTATTACTGT GCTACACGCC ACGACCCTCC ACTGAAGAGG TCTGCTTCCA ACAAAGTGCC TGCCATGCAG AGAACCATGC GCACACGCAA GCGCAGAAAG ATGTATGAGA TGTGCCTACC TGAGCAGGAA CAAAGGCCTC CACTGGTTCA GCAGAGATTT CTTGACGTAG CCAACCTCAA TAATCCTTGT ACCTCCACTC AAGAACCCAC AGAAGGGCTA GGAGAGTGCT ACCACCCAAG ATGTGATATC TTTCCAGGAA TTGTCTCTAA ACACTTGGAA ACTTCTCTGA CGATCAACAA GTGTGTTCCA GTTTCCAAAT GTGATACTAC TCATTCCAGT GTTTCCTGCC TAGAGATGGA CGTGCCCATA GATCTCAGCA AAAAGTGTTT ATCTCAGTCT GAGCGGACGA CCACGTCTCC CAAAAGGCTG CTGGACTATC ACGAGTGCAC TGTGTGCAAG ATCAGTTTCA ATAAGGTAGA AAACTATCTG GCCCACAAGC AGAATTTCTG CCCGGTTACT GCACATCAGC GTAATGACCT GGGTCAACTG GACGGCAAAG TGTTTCCGAA TCCAGAAAGC GAACGAAACA GCCCTGATGT CAGCTACGAA AGAAGCATAA TAAAATGTGA GAAAAATGGG AATTTGAAGC AGCCTTCCCC CAATGGAAAC TTATTTTCAT CCCACCTAGC AACCCTGCAA GGCTTGAAGG TCTTTAGTGA AGCTGCTCAG CTCATTGCTA CAAAAGAAGA AAACAGACAT TTGTTTCTTC CACAATGCCT TTACCCTGGA GCAATAAAGA AAGCAAAAGG AGCCGACCAG CTTTCTCCAT ATTATGGAAT CAAGCCAAGT GATTATATTT CTGGTTCTCT TGTCATCCAT AACACTGACA TCGAGCAAAG CAGAAATGCA GAAAATGAAT CTCCTAAAGG CCAGGCTTCC TCAAATGGGT GTGCTGCGCT GAAGAAAGAT TCTCTGCCAT TGTTGCCCAA AAATCGAGGA ATGGTAATAG TGAATGGTGG ACTGAAACAA GATGAGAGAC CTGCTGCCAA CCCACAGCAA GAGAACATTT CCCAGAATCC TCAGCACGAA GACGACCACA AATCTCCCTC GTGGATCTCT GAGAACCCAT TAGCTGCCAA TGAGAATGTC TCACCAGGAA TTCCCTCAGC AGAGGAACAG TTGTCTAGTA TAGCAAAAGG TGTGAATGGT TCCAGCCAGG CTCCAACCAG TGGGAAATAT TGCCGGCTAT GTGATATCCA GTTCAACAAC CTTTCAAACT TTATAACTCA CAAGAAGTTT TATTGCTCAT CACATGCAGC AGAACATGTC Protein function: Transcription regulator that plays a central role in heart morphogenesis and development of coronary vessels from epicardium, by regulating genes that are essential during cardiogenesis. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA4, GATA5 and GATA6. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. Also required in gonadal differentiation, possibly be regulating expression of SRY. Probably acts a corepressor of NR2F2. [The UniProt Consortium]