ZDHHC20 (Vector pUC, Accession No. BC110517)

Length: 963 Sequence: ATGGCGCCCT GGACGCTGTG GCGCTGCTGC CAGCGCGTCG TGGGCTGGGT GCCGGTGCTC TTCATCACCT TCGTGGTCGT CTGGTCCTAC TACGCGTACG TGGTGGAGCT CTGCGTGTTT ACTATTTTTG GAAATGAAGA AAATGGAAAG ACCGTTGTTT ACCTTGTGGC TTTCCATCTG TTCTTTGTTA TGTTTGTATG GTCCTATTGG ATGACAATTT TCACATCTCC CGCTTCCCCC TCCAAAGAGT TCTACTTGTC CAATTCTGAA AAGGAACGTT ATGAAAAAGA ATTCAGCCAA GAAAGACAAC AAGAAATTTT GAGAAGAGCA GCAAGAGCTT TACCTATCTA TACCACATCA GCTTCAAAAA CTATCAGATA TTGTGAAAAA TGTCAGCTGA TTAAACCTGA TCGGGCGCAT CACTGCTCAG CCTGTGACTC ATGTATTCTT AAGATGGATC ATCACTGTCC TTGGGTGAAT AACTGTGTGG GATTTTCTAA TTACAAATTC TTCCTGCTGT TTTTATTGTA TTCCCTATTA TATTGCCTTT TCGTGGCTGC AACAGTTTTA GAGTACTTTA TAAAATTTTG GACGAATGAA CTGACAGATA CACGTGCAAA ATTCCACGTA CTTTTTCTTT TCTTTGTGTC TGCAATGTTC TTCATCAGCG TCCTCTCACT TTTCAGCTAC CACTGCTGGC TAGTTGGAAA AAATAGAACA ACAATAGAAT CATTCCGCGC ACCCACGTTT TCATACGGAC CTGATGGAAA TGGTTTCTCT CTTGGATGCA GTAAAAATTG GAGACAAGTC TTTGGTGATG AAAAGAAATA TTGGCTACTT CCAATATTTT CAAGCTTGGG TGATGGTTGC AGTTTTCCAA CTCGCCTTGT GGGGATGGAT CCAGAACAAG CTTCTGTTAC AAACCAGAAT GAGTATGCCA GAAGATCTAA ACTGCAGAGG Protein function: Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates (PubMed:27153536, PubMed:29326245). Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation (PubMed:27153536). Has a preference for acyl-CoA with C16 fatty acid chains (PubMed:29326245). Can also utilize acyl-CoA with C14 and C18 fatty acid chains (PubMed:29326245). [The UniProt Consortium]