USP6NL (Vector pUC, Accession No. BC042943)

Length: 2487 Sequence: atgaattcag accaggatgt agcactcaaa cttgcccagg agcgagctga aatagttgct aaatatgaca gaggacgaga aggtgcagag attgaacctt gggaagatgc tgattacctt gtttacaaag tcacagatag atttggcttt ttacatgagg aggagctccc agatcataat gtggctgtgg aacggcaaaa gcacctggaa attgaaagaa ctaccaaatg gctgaaaatg ctgaaaggat gggaaaaata caagaacact gaaaagtttc ataggcgaat ttacaaagga ataccactcc agctcagagg tgaagtctgg gccctccttc ttgagatccc taaaatgaaa gaagaaacaa gggacctgta tagtaaatta aaacacagag cacggggctg ttcacctgac atcagacaaa tagacctgga tgtcaaccgc acatttcggg accacattat gtttagagac agatatggtg ttaagcaaca atccttattc catgtgcttg ctgcctattc tatttataac acggaagtcg ggtattgtca ggggatgagc cagatcacag ctttactcct catgtatatg aacgaggaag atgccttctg ggccctggtc aaactcttct caggccctaa acatgccatg catggctttt ttgtccaagg ttttcctaaa ctcttgaggt ttcaagaaca tcatgaaaaa atactgaaca aatttctgtc caagcttaag caacacttgg attctcaaga aatctacaca agtttttaca caatgaaatg gttttttcag tgtttccttg atcgtactcc ctttacacta aacctcagaa tatgggatat ctacatcttt gaaggagaac gagttcttac tgctatgtct tacaccatct taaaattaca caaaaaacat ctaatgaaat tgtccatgga agaacttgta gaattttttc aggagaccct ggcaaaggat tttttctttg aagatgattt tgtgatagag caacttcaga tttctatgac agaactaaag cgggcaaagt tagaccttcc agaacctggt aaagaggatg aatatccaaa gaagcccttg gggcagcttc cacctgaact tcagtcttgg ggcgtccatc acttgagcaa cggacagagg agcgtgggcc ggccgagccc gctggccagc ggcaggaggg agagcggggc gccccacagg aggcacgagc actccccgca cccccagagc aggaccggga cgcccgagag agcacagccg ccaagacgga aatcggtgga ggaggagagc aaaaagctta aagatgaggc agattttcaa agaaaactcc catcgggtcc acaggacagt tccaggcaat ataatcacgc agctgccaac caaaatagca acgccacttc aaatatcagg aaggagtttg tgcccaaatg gaataaaccg tcagacgtct cagctacaga gagaactgcc aaatacacca tggaaggcaa aggtcgagca gcgcaccccg cgctcgcagt taccgtccca ggtcctgccg aggtgcgggt gtcaaacgtg cggccaaaga tgaaggccct ggatgctgag gacgggaagc ggggctccac tgcatcgcag tacgacaacg tgccaggccc ggagctggac agcggcgctt ccgtggagga ggcgctggaa agggcttact cccagagccc ccggcatgcc ctttaccctc ctagcccgag aaagcacgct gagccaagtt ctagtccatc aaaagtatcc aacaagttta cttttaaagt acagcctcca agtcatgcac gatatccgtc ccagctagat ggggaagccc gagggctagc tcatcccccc tcctacagca atccccccgt ttaccacgga aactctccca aacacttccc tactgccaac agcagctttg cttctccaca gtttagccct gggactcaac tgaatccttc caggagacct catggttcta ctctttccgt cagtgcttct ccggagaaat cttacagccg cccaagcccc cttgtactgc cgtctagtcg aatagaagtc ctccctgttg acactggtgc tgggggatat tcgggcaatt cagggtcacc aaagaatgga aaattgatca ttccaccagt ggattacttg ccagataaca gaacatggtc agaagttagt tatacataca gacctgagac gcagggacaa tcatggaccc gagatgctag ccgtggcaat ttaccaaaat actcagcctt tcaactcgca ccctttcagg accatggcct ccctgcagtt tctgtagata gtcccgtgag atataaagct tcaccggccg cagaagatgc cagtccatct ggatatccat attcagggcc cccgcctcca gcctaccact acaggaatcg ggacgggctt tccatccaag agtcagtgtt Protein function: Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex. [The UniProt Consortium]