TKTL2 (Vector pUC, Accession No. BC028707)

Length: 1881 Sequence: atgatggcca acgacgccaa gcccgacgtg aagaccgtgc aggtgctgcg ggacacagcc aaccgcctgc ggatccattc catcagggcc acgtgtgcct ctggttctgg ccagctcacg tcgtgctgca gtgcagcgga ggtcgtgtct gtcctcttct tccacacgat gaagtataaa cagacagacc cagaacaccc ggacaacgac cggttcatcc tctccagggg acatgctgct cctatcctct atgctgcttg ggtggaggtg ggtgacatca gtgaatctga cttgctgaac ctgaggaaac ttcacagcga cttggagaga caccctaccc cccgattgcc gtttgttgac gtggcaacag ggtccctagg tcagggatta ggtactgcat gtggaatggc ttatactggc aagtaccttg acaaggccag ctaccgggtg ttctgcctta tgggagatgg cgaatcctca gaaggctctg tgtgggaggc ttttgctttt gcctcccact acaacttgga caatctcgtg gcggtcttcg acgtgaaccg cttgggacaa agtggccctg caccccttga gcatggcgca gacatctacc agaattgctg tgaagccttt ggatggaata cttacttagt ggatggccat gatgtggagg ccttgtgcca agcattttgg caagcaagtc aagtgaagaa caagcctact gctatagttg ccaagacctt caaaggtcgg ggtattccaa atattgagga tgcagaaaat tggcatggaa agccagtgcc aaaagaaaga gcagatgcaa ttgtcaaatt aattgagagt cagatacaga ccaatgagaa tctcatacca aaatcgcctg tggaagactc acctcaaata agcgtcacag atataaaaat gacctcccca catgcttaca aagttggtga caagatagct actcagaaaa catatggttt ggctctggct aaactgggcc gtgcaaatga aagagttatt gttctgagtg gtgacacgat gaactccacc ttttctgaga tattcaggaa agaacaccct gagcgtttca tagagtgtat tattgctgaa caaaacatgg taagtgtggc actaggctgt gctacacgtg gtcgaaccat tgcttttgct ggtgcttttg ctgccttttt tactagagca ttcgatcagc tccgaatggg agccatttct caagccaata tcaaccttat tggttcccac tgtggggtat ccactggaga agatggagtc tcccagatgg ccctggagga tctagccatg ttccgaagca ttcccaattg tactgttttc tatccaagtg atgccatctc gacagagcat gctatttatc tagccgccaa taccaaggga atgtgcttca ttcgaaccag ccaaccagaa actgcagtta tttatacccc acaagaaaat tttgagattg gccaggccaa ggtggtccgc cacggtgtca atgataaagt cacagtaatt ggagctggag ttactctcca tgaagcctta gaagctgctg accatctttc tcaacaaggt atttctgtcc gtgtcatcga cccatttacc attaaacccc tggatgccgc caccatcatc tccagtgcaa aagccacagg cggccgagtt atcacagtgg aggatcacta cagggaaggt ggcattggag aagctgtttg tgcagctgtc tccagggagc ctgatatcct tgttcatcaa ctggcagtgt caggagtgcc tcaacgtggg aaaactagtg aattgctgga tatgtttgga atcagtacca gacacattat agcagccgta acacttactt taatgaagta Protein function: Plays an essential role in total transketolase activity and cell proliferation in cancer cells, after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis. [The UniProt Consortium]