TENC1 (Vector pUC, Accession No. BC129828)

Length: 3858 Sequence: ATGGAGCGGC GCTGGGACTT AGACCTCACC TACGTGACGG AGCGCATCTT GGCCGCCGCC TTCCCCGCGC GGCCCGATGA ACAGCGGCAC CGGGGCCACC TGCGCGAGCT GGCCCATGTG CTGCAATCCA AGCACCGGGA CAAGTACCTG CTCTTCAACC TTTCAGAGAA AAGGCATGAC CTGACCCGCT TAAACCCCAA GGTTCAAGAC TTCGGCTGGC CTGAGCTGCA TGCTCCACCC CTGGACAAGC TGTGCTCCAT CTGCAAAGCC ATGGAGACAT GGCTCAGTGC TGACCCACAG CACGTGGTCG TACTATACTG CAAGGGAAAC AAGGGCAAGC TTGGGGTCAT CGTTTCTGCC TACATGCACT ACAGCAAGAT CTCTGCAGGG GCGGACCAGG CACTGGCCAC TCTTACCATG CGGAAATTCT GCGAGGACAA GGTGGCCACA GAACTGCAGC CCTCCCAGCG TCGATATATC AGCTACTTCA GTGGGCTGCT ATCTGGCTCC ATCAGAATGA ACAGCAGCCC TCTCTTCCTG CACTATGTGC TCATCCCCAT GCTGCCAGCC TTTGAACCTG GCACAGGCTT CCAGCCCTTC CTTAAAATCT ACCAGTCCAT GCAGCTTGTC TACACATCTG GAGTCTATCA CATTGCAGGC CCTGGTCCCC AGCAGCTTTG CATCAGCCTG GAGCCAGCCC TCCTCCTCAA AGGCGATGTC ATGGTAACAT GTTATCACAA GGGTGGCCGG GGCACAGACC GGACCCTCGT GTTCCGAGTC CAGTTCCACA CCTGCACCAT CCACGGACCA CAGCTCACTT TCCCCAAGGA CCAGCTTGAC GAGGCCTGGA CTGATGAGAG GTTCCCCTTC CAAGCCTCCG TGGAGTTTGT CTTCTCCTCC AGCCCCGAGA AGATCAAAGG CAGCACTCCA CGGAACGACC CCTCGGTCTC TGTCGACTAC AACACCACTG AGCCAGCCGT GCGCTGGGAC TCCTATGAGA ACTTCAACCA GCACCACGAG GACAGTGTGG ATGGCTCCTT GACCCACACC CGGGGTCCCC TGGATGGCAG TCCTTATGCC CAGGTGCAGC GGCCTCCCCG GCAGACCCCC CCGGCACCCT CTCCAGAGCC TCCACCACCC CCCATGCTCT CTGTCAGCAG CGACTCAGGC CATTCCTCCA CGCTGACCAC AGAGCCGGCT GCTGAGTCCC CTGGCCGGCC GCCCCCTACA GCTGCTGAAC GGCAGGAGCT GGATCGCCTC CTAGGAGGCT GCGGAGTGGC CAGTGGGGGC CGGGGAGCTG GGCGCGAGAC GGCCATCCTA GATGACGAAG AGCAGCCCAC TGTGGGCGGA GGCCCCCACC TCGGAGTGTA TCCAGGCCAT AGGCCTGGCC TCAGCCGCCA CTGCTCCTGC CGCCAGGGCT ACCGGGAGCC CTGCGGGGTT CCCAATGGGG GCTACTACCG GCCAGAGGGA ACCCTGGAGA GGAGGCGACT GGCCTACGGG GGCTATGAGG GATCCCCCCA GGGCTACGCC GAGGCCTCGA TGGAGAAGAG GCGCCTCTGC CGATCGCTGT CAGAGGGGCT ATACCCCTAC CCACCTGAGA TGGGGAAACC AGCCACTGGG GACTTTGGCT ACCGCGCCCC AGGCTACCGG GAGGTGGTCA TCCTGGAGGA CCCTGGGCTG CCTGCCCTAT ACCCATGCCC AGCCTGCGAG GAGAAGCTGG CGCTGCCTAC AGCAGCCTTG TATGGACTGC GGCTGGAGAG GGAGGCTGGA GAAGGGTGGG CAAGTGAGGC TGGCAAGCCT CTCCTGCACC CAGTGCGGCC TGGGCACCCG CTGCCTCTGC TCTTGCCTGC CTGTGGGCAT CACCATGCCC CGATGCCTGA CTACAGCTGC CTGAAGCCAC CCAAGGCAGG CGAGGAAGGG CACGAGGGCT GCTCCTACAC CATGTGCCCC GAAGGCAGGT ATGGGCATCC AGGGTACCCT GCCCTGGTGA CATACAGCTA TGGAGGAGCA GTTCCCAGTT ACTGCCCAGC ATATGGCCGT GTGCCTCATA GCTGTGGCTC TCCAGGAGAG GGCAGAGGGT ATCCCAGCCC TGGTGCCCAC TCCCCACGGG CTGGCTCCAT TTCCCCGGGC AGCCCGCCCT ATCCACAATC TAGGAAGCTG AGCTACGAGA TCCCTACGGA GGAGGGAGGG GACAGGTACC CATTGCCTGG GCACCTGGCC TCAGCAGGAC CTTTGGCATC TGCAGAGTCG CTGGAGCCGG TGTCCTGGAG GGAGGGCCCC AGTGGGCACA GCACACTGCC TCGGTCTCCC CGAGATGCCC CATGCAGTGC TTCGTCAGAG TTGTCTGGTC CCTCCACGCC CCTGCACACC AGCAGTCCAG TCCAGGGCAA GGAAAGCACC CGGCGACAGG ACACCAGGTC CCCCACCTCA GCGCCCACTC AGAGACTGAG TCCTGGCGAG GCCTTGCCCC CTGTTTCCCA GGCAGGCACC GGAAAGGCCC CTGAGCTGCC GTCGGGAAGT GGGCCTGAGC CTCTGGCCCC TAGCCCAGTC TCTCCGACCT TCCCTCCCAG CTCGCCCAGT GACTGGCCTC AGGAAAGGAG TCCAGGGGGC CACTCAGATG GCGCCAGTCC TCGGAGCCCT GTGCCCACCA CACTTCCTGG CCTCCGCCAC GCCCCCTGGC AAGGCCCTCG AGGCCCCCCC GACAGCCCAG ATGGGTCTCC CCTCACTCCT GTGCCTTCCC AGATGCCCTG GCTTGTGGCC AGCCCAGAGC CGCCTCAGAG CTCACCTACA CCTGCTTTCC CCCTGGCTGC CTCCTATGAC ACCAATGGCC TTAGCCAGCC CCCACTTCCT GAGAAACGCC ACCTGCCCGG GCCGGGGCAA CAGCCAGGAC CCTGGGGCCC AGAGCAGGCA TCATCGCCAG CCAGAGGCAT CAGTCACCAT GTCACCTTCG CACCTCTGCT CTCAGATAAT GTCCCCCAAA CCCCAGAGCC TCCTACACAA GAGAGCCAAA GCAATGTCAA GTTTGTCCAG GATACATCCA AGTTCTGGTA CAAGCCACAC CTGTCCCGTG ACCAAGCCAT TGCCCTGCTG AAGGACAAGG ACCCTGGGGC CTTCCTGATC AGGGACAGTC ATTCATTCCA AGGAGCTTAT GGGCTGGCCC TCAAGGTGGC CACACCGCCA CCCAGTGCCC AGCCCTGGAA AGGGGACCCC GTGGAACAGC TGGTCCGCCA TTTCCTCATC GAGACTGGGC CCAAAGGGGT GAAGATCAAG GGCTGCCCCA GTGAGCCCTA CTTTGGCAGC CTGTCCGCCT TGGTCTCCCA GCACTCCATC TCCCCCATCT CCCTGCCCTG CTGCCTGCGC ATTCCCAGCA AAGATCCTCT GGAAGAGACC CCAGAGGCTC CAGTGCCCAC CAACATGAGC ACAGCGGCAG ACCTCCTGCG TCAGGGTGCT GCCTGCAGCG TGCTCTACTT GACCTCAGTG GAGACAGAGT CACTGACGGG CCCCCAAGCT GTGGCCCGGG CCAGCTCTGC AGCTCTGAGC TGTAGCCCCC GCCCGACACC AGCTGTTGTC CACTTCAAGG TGTCAGCCCA GGGCATTACA CTGACGGACA ACCAAAGGAA GCTCTTCTTT CGCCGCCATT ATCCAGTGAA CAGCATCACC TTCTCCAGCA CTGACCCTCA AGACCGGAGA TGGACCAACC CAGACGGGAC CACCTCCAAG ATCTTTGGTT TCGTGGCCAA GAAGCCGGGA AGCCCCTGGG AGAATGTGTG TCACCTCTTT GCAGAGCTTG ACCCAGATCA GCCTGCTGGC GCCATTGTCA CCTTCATCAC CAAAGTTCTA CTGGGCCAGA Protein function: Tyrosine-protein phosphatase which regulates cell motility proliferation and muscle-response to insulin (PubMed:15817639, PubMed:23401856). In muscles and under catabolic conditions, dephosphorylates IRS1 leading to its degradation and muscle atrophy (PubMed:23401856). Negatively regulates PI3K-AKT pathway activation (PubMed:15817639, PubMed:23401856). [The UniProt Consortium]