SEC24D (Vector pUC, Accession No. BC035761)

Length: 3102 Sequence: atgagtcaac aaggttacgt ggctacacct ccgtattctc agcctcagcc tggaataggc ctttctccac ctcattatgg gcactatggg gatccgtcgc acacagcatc tccaacaggt atgatgaagc cagcagggcc tttgggggcc accgccacta ggggaatgtt gcctccgggt cccccacctc ctggacccca tcagtttggt cagaatggag ctcatgccac tggtcaccct ccccaaagat ttccaggccc tccacctgtc aacaatgtgg catcctcaca tgcaccatac caaccctctg cacaatcttc ttatccaggt cctatatcca cttcatctgt cacccagctg ggcagccagc tcagtgctat gcaaatcaac agctatggtt caggcatggc tcctccaagc cagggacccc ctggccctct gtcagccaca tcattgcaga ctcctccacg acctccacag ccttccattt tgcagcctgg atctcaagtt cttccaccac cacccaccac actcaatggt cctggtgcct cacctttgcc tctaccaatg tacagaccag atgggctctc tgggcctcct cctccaaatg cccagtacca gcccccacct cttccaggcc agaccttggg tgctggatat cctccgcagc aggcagccaa ctctggtccc cagatggcag gcgcacaact gtcttaccca ggaggcttcc ctggaggtcc tgcacagatg gctggtccgc cacagcccca gaagaagctg gatcctgact ctatccctag cccaatccag gtgattgaga atgatagagc cagcagagga ggacaagttt atgccaccaa caccagaggc cagatccctc ccctggtcac tacagattgc atgatacaag accaaggaaa tgccagtcct cgattcatcc gttgtacaac atactgtttt ccatgcacgt cagatatggc taagcaagct cagattccat tagctgctgt catcaagccc tttgccacca ttccttcaaa tgagagtccc ctttacttgg taaatcacgg cgagagtgga ccagtcagat gcaacaggtg caaggcctac atgtgcccat ttatgcagtt catcgaagga ggaaggagat atcagtgtgg attttgcaac tgtgtgaatg atgttccacc attctatttc caacatctgg accacattgg aagaagactg gaccactatg agaaaccaga gttatctcta ggatcttatg aatatgttgc cactttggat tattgcagaa agagtaagcc tcccaaccca ccagccttta tcttcatgat tgatgtttca tatagtaaca taaagaatgg acttgtcaag ctcatatgtg aagaactgaa gaccatgctg gaaaaaattc caaaggaaga gcaagaagag acgtctgcaa ttcgagtggg ttttatcaca tataacaaag ttctccattt ctttaatgtg aagagtaatc tggcccagcc tcagatgatg gtggtgactg atgttggaga agtctttgtt cctttgttgg atggtttcct tgtcaactat caagaatccc aatctgtgat tcataatttg ttggaccaga ttccagacat gtttgcagac tctaatgaaa atgagactgt ctttgctcct gtcatccagg ctggcatgga agcactaaag gcagcagact gtcctgggaa gctgttcatc ttccattctt ccttgccaac tgctgaagca ccagggaagc tcaaaaacag agatgacaaa aaactggtta atacagacaa agagaagata cttttccagc cccaaacaaa tgtctatgac tcattggcca aggactgcgt ggctcacggc tgctctgtga cactcttcct ctttcctagt cagtatgtgg acgtggcctc gctggggctg gttcctcagc tcactggagg aaccctttac aaatacaaca atttccagat gcacttggat agacaacaat ttttgaacga cctcagaaat gatattgaaa agaaaatagg ctttgatgct attatgaggg ttcgtaccag cacaggtttc agagccactg atttctttgg tggaatcttg atgaacaaca ccaccgatgt agaaatggct gccatcgatt gtgacaaggc agtgaccgtg gagttcaagc acgatgacaa actcagtgaa gacagtggag ccttaatcca gtgtgctgtg ctttacacga caatcagtgg tcaaagaaga cttcggattc acaatcttgg cttaaactgc agctctcagc tagctgatct ttataagagc tgtgagacag atgctcttat caacttcttt gccaagtcag cttttaaagc agttcttcac cagcctttga aggtcatccg ggaaattcta gttaatcaga ctgcccatat gttggcatgt taccggaaga attgtgcaag tccttctgca gcaagccagc ttattctacc agattccatg aaagtattgc cagtgtacat gaattgcttg ttgaaaaact gtgtactact cagcagacca gagatctcaa ctgatgaacg agcataccag agacagctgg tcatgaccat gggtgtggct gactctcagc ttttcttcta cccacaactt ctgcccatac acacgttaga tgtcaagagt acaatgttac ctgctgccgt tcgttgctct gagtcccgtc tttcagaaga aggaatattc ttactggcta atggtctaca catgttcctg tggttgggag taagcagccc accagaactg atccaaggaa tatttaatgt gccatctttt gcacatatca acacagatat gacattgctg cctgaagtgg gaaacccata ctctcaacaa ctcagaatga taatgggtat tatccaacaa aagaggccat attcaatgaa gctcacaatt gtaaagcagc gagaacaacc agaaatggtt ttccgacagt tcctggtaga agacaaagga ctttacggag gctcttctta tgtggatttc ctttgttgtg ttcacaagga gatctgtcag ctgcttaatt Protein function: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (PubMed:17499046, PubMed:20427317, PubMed:18843296). Plays a central role in cargo selection within the COPII complex and together with SEC24C may have a different specificity compared to SEC24A and SEC24B (PubMed:17499046, PubMed:20427317, PubMed:18843296). May more specifically package GPI-anchored proteins through the cargo receptor TMED10 (PubMed:20427317). May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5 (PubMed:18843296). [The UniProt Consortium]