POLR2C (Vector pUC, Accession No. BC003159)

Length: 828 Sequence: atgccgtacg ccaaccagcc taccgtgcgg atcacggagc tcactgacga gaatgtcaag ttcatcatcg agaacaccga cctggcggtg gccaattcga ttcggagggt cttcatcgct gaggttccca taatagccat tgactgggtt cagattgatg ccaattcctc agttcttcat gatgaattca ttgctcacag gcttggatta attcccctca ttagtgatga cattgtggac aagctgcagt actctcggga ctgcacatgt gaggagttct gccccgagtg ctcggtggag ttcaccctcg atgtgcggtg caatgaagac cagacgcgac atgtcacgtc tcgagacctc atctccaaca gcccccgggt cattccggtg acatcccgga accgagataa tgaccccaat gactacgtgg agcaggatga catcctcatc gtcaagttga gaaagggcca ggagctgaga cttcgagcct atgccaaaaa gggctttggc aaggagcatg ccaagtggaa ccctactgca ggggtggctt ttgaatacga tccagacaat gccctgaggc acacagtgta ccccaagccc gaggaatggc caaagagtga gtactcggag ctggatgagg atgagtcgca ggctccctat gaccccaacg gcaagccaga aaggttttac tacaatgtgg agtcctgtgg ctctctgcgt cctgaaacca ttgtcctgtc agccctctca ggattgaaga agaaactgag tgatttacaa actcaattaa gccacgagat ccagagtgat gtgctaacca Protein function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft. [The UniProt Consortium]