PHF15 (Vector pUC, Accession No. BC021962)

Length: 2376 Sequence: atggaagaga agaggcgaaa atactccatc agcagtgaca actctgacac cactgacagt catgcgacat ctacatccgc atcaagatgc tccaaactgc ccagcagcac caagtcgggc tggccccgac agaacgaaaa gaagccctcc gaggttttcc ggacagactt gatcacagcc atgaagatcc cggactcata ccagctcagc ccggatgact actacatcct ggcagaccca tggcgacagg aatgggagaa aggtgtgcag gtgcctgccg gggcagaggc catcccagag cccgtggtga ggatcctccc accactggaa ggcccccctg cccaggcatc cccgagcagc accatgcttg gtgagggctc ccagcctgat tggccagggg gcagccgcta tgacttggac gagattgatg cctactggct ggagctcatc aactcggagc ttaaggagat ggagaggccg gagctggacg agctgacatt agagcgtgtg ctggaggagc tggagaccct gtgccaccag aatatggcca gggccattga gacgcaggag gggctgggca tcgagtacga cgaggatgtt gtctgcgacg tgtgtcgctc tcctgagggc gaggatggca acgagatggt cttctgtgac aagtgcaacg tctgtgtgca tcaggcatgc tacgggatcc tcaaggtgcc cacgggcagc tggctgtgcc ggacgtgtgc cctgggtgtc cagccaaagt gcctgctctg ccccaagcga ggaggagcct tgaagcccac tagaagtggg accaagtggg tgcatgtcag ctgtgcccta tggattcctg aggtcagcat cggctgccca gagaagatgg agcccatcac caagatctcg catatcccag ccagccgctg ggctctgtcc tgcagcctct gcaaggaatg cacaggcacc tgcatccagt gttccatgcc ttcctgcgtc acagcgttcc atgtcacatg cgcctttgac cacggcctgg aaatgcggac tatattagca gacaacgatg aggtcaagtt caagtcattc tgccaggagc acagtgacgg gggcccacgt aatgagccca catctgagcc cacggaaccc agccaggctg gcgaggacct ggaaaaggtg accctgcgca agcagcggct gcagcagcta gaggaggact tctacgagct ggtggagccg gctgaggtgg ctgagcggct ggacctggct gaggcactgg tcgacttcat ctaccagtac tggaagctga agaggaaagc caatgccaac cagccgctgc tgacccccaa gaccgacgag gtggacaacc tggcccagca ggagcaggac gtcctctacc gccgcctgaa gctcttcacc catctgcggc aggacctaga gagggttaga aatctgtgct acatggtgac aaggcgcgag agaacgaaac acgccatctg caaactccag gagcagatat tccacctgca gatgaaactt attgaacagg atctgtgtcg agcaggcctg tccacctcat tccccatcga tggcaccttc ttcaacagct ggctggcaca gtcggtgcag atcacagcag agaacatggc catgagcgag tggccactga acaatgggca ccgcgaggac cctgctccag ggctgctgtc agaggaactg ctgcaggacg aggagacact gctcagcttc atgcgggacc cctcgctgcg acctggtgac cctgctagga aggcccgagg ccgcacccgc ctgcctgcca agaagaaacc accaccacca ccaccgcagg acgggcctgg ttcacggacg actccagaca aagcccccaa gaagacctgg ggccaggatg caggcagtgg caaggggggt caagggccac ctaccaggaa gccaccacgt cggacatctt ctcacttgcc gtccagccct gcagccgggg actgtcccat cctagccacc cctgaaagcc ccccgccact ggcccctgag accccggacg aggcagcctc agtagctgct gactcagatg tccaagtgcc tggccctgca gcaagcccta agcctttggg ccggctccgg ccaccccgcg agagcaaggt aacccggaga ttgccgggtg ccaggcctga tgctgggatg ggaccacctt cagctgtggc tgagaggccc aaggtcagcc tgcattttga cactgagact gatggctact tctctgatgg ggagatgagc gactcagatg tagaggccga ggacggtggg gtgcagcggg gtccccggga ggcaggggca gaggaggtgg tccgcatggg cgtactggcc Protein function: Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity (PubMed:16387653). Acts as a E3 ubiquitin-protein ligase mediating the ubiquitination and subsequent proteasomal degradation of target protein histone demethylase KDM1A (PubMed:25018020). Also acts as a ubiquitin ligase E3 toward itself. Positive regulator of neurogenesis. [The UniProt Consortium]