NPHP3 (Vector pUC, Accession No. BC068082)

Length: 453 Sequence: atggggaccg cctcgtcgct cgtgagcccc gcgggcgggg aagtgatcga ggacacgtac ggggcgggcg gcggcgaggc ctgcgagatc ccggtggagg tgaagcccaa ggcccgcctg ctgcgcaact cgttccgccg aggcgcgggg gcggcagcag gggccgggcc cgggtcgctg ccccgcgggg tgggcgcggg cgggctgctg ggggccagct tcaagtccac tggctcgtcg gtgccagagc tggagtacgc ggcggccgag tacgagcggc tcaggaagga gtacgagatc tttcgcgtca gcaagaacca ggagttgttg tccatgggcc gccgcgaggc caagctggac acggagaaca agcggctgcg ggccgaactg cagggtctcg ctgcggtggc acgatcgcgg ctcactgcaa cctggaactc ctgggctcaa Protein function: Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements. [The UniProt Consortium]