LZTS2 (Vector pUC, Accession No. BC058938)

Length: 2010 Sequence: atggccattg tgcagactct gccagtgcca ctggagcctg ctcctgaagc tgccactgcc ccacaagctc cagtcatggg tagtgtgagc agccttatct caggccggcc ctgtcccggg gggccagctc ctccccgcca ccacggccct cctgggccca ccttcttccg ccagcaggat ggcctgctac ggggtggcta tgaggcacag gagccgctgt gcccagctgt gccccctagg aaggctgtcc ctgtcaccag cttcacctac atcaatgagg acttccggac agagtcaccc cccagcccaa gcagtgatgt tgaggatgcc cgagagcagc gggcacacaa tgcccacctc cgcggcccac caccaaagct catccctgtc tctggaaagc tggagaagaa catggagaag atcctgatcc gcccaacagc cttcaagcca gtgctgccca aacctcgagg ggctccgtcc ctgcctagct tcatgggtcc tcgggccacc gggctgtctg ggagccaggg cagcctgacg cagctgtttg ggggccctgc ctcctcctcc tcctcttcct cctcctcttc agctgctgac aaacccctgg catttagtgg ctgggccagt ggctgcccat cagggacgct atccgactct ggccgaaact cactgtccag cctgcccacc tacagcaccg gaggtgccga gccaaccacc agctccccag gcgggcacct gccttcccat ggctctgggc gaggggcact gcctgggcca gcccgagggg tccctactgg gccctcccac tcagacagtg gccggtcctc ctccagcaag agcacaggct ccctaggggg ccgtttggct ggggggcttt tgggcagtgg tactcgggcc tcccctgaca gcagctcctg tggggagcgc tcaccaccac ccccgcctcc acctccttcg gatgaggccc tgctgcactg tgtcctggaa ggaaagctcc gagaccggga ggcagagctt cagcagctgc gggacagtct ggacgagaat gaggctacca tgtgccaggc atacgaggag cggcagcggc actggcagcg agagcgtgag gccctgcgag aggactgtgc ggcccaggca cagcgggcac agcgggccca acagctgctg cagctgcagg tgttccagct gcagcaggag aagcggcaat tgcaggatga cttcgcacag ctgctgcagg agcgcgaaca gctggagcgg cgctgcgcca ccttggagcg ggagcagcgg gagctcgggc cgaggcttga ggagaccaag tgggaggtgt gccagaaatc aggcgagatc tccctgctga agcagcagct gaaagagtct caggcagagc tggtgcagaa gggcagcgag ctggtggctc tgcgggtggc gctgcgggag gcccgtgcta cgctgcgggt cagtgagggc cgtgcgcggg gtctacagga ggccgcccga gctcgggagc tggagctgga agcctgttcc caggagctgc agcgacaccg ccaggaagct gagcagctgc gggagaaagc tgggcagttg gatgctgagg cggccggact ccgggagccc cctgtgccac ctgccaccgc tgacccattc ctcctggcgg agagtgatga ggccaaagtg cagcgggcag cagccggggt tgggggcagc ttgcgggccc aggtggagcg attgcgggtg gagctgcagc gggagcggcg gcggggtgag gagcagcggg acagctttga gggggagcgg ctggcctggc aggcagagaa ggagcaggtg atccgctacc agaagcagct gcagcacaac tacatccaga tgtaccggcg caaccggcag ctagagcagg agctgcagca gctcagcctg gagctggagg cccgggagct cgctgacctg ggcctggccg agcaggcccc ctgcatctgc ctggaggaga tcactgctac Protein function: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. [The UniProt Consortium]