KLHDC8B (Vector pUC, Accession No. BC039083)

Length: 1065 Sequence: atgtctgcag gaggtggccg ggcctttgct tggcaagtgt tcccccccat gcccacttgc cgggtctatg gcacagtggc acaccaagat gggcacctgc tggtgttggg gggttgtggc cgggctggac tgcccctgga cactgctgag acactggaca tggcctcgca cacatggctg gcactggcac ccctgcccac tgcccgggct ggtgcagctg cggtagttct gggcaagcag gtgctagtgg tgggtggtgt ggatgaggtc cagagcccgg tagctgctgt agaggccttc ctgatggatg agggccgctg ggagcgtcgg gccaccctcc ctcaagcagc catgggggtt gcaactgtgg agagagatgg tatggtgtat gctctggggg gaatgggccc tgacacggcc ccccaggccc aggtacgtgt gtatgagccc cgtcgggact gctggctttc gctaccctcc atgcccacac cctgctatgg ggcctccacc ttcctgcacg ggaacaagat ctatgtcctg gggggccgcc agggcaagct cccggtgact gcttttgaag cctttgatct ggaggcccgt acatggaccc ggcatccaag cctacccagc cgtcgggcct ttgctggctg cgccatggct gaaggcagcg tctttagcct gggtggcctg cagcagcctg ggccccacaa cttctactct cgcccacact ttgtcaacac tgtggagatg tttgacctgg agcatgggtc ctggaccaaa ttgccccgca gcctgcgcat gagggataag agggcagact ttgtggttgg gtcccttggg ggccacattg tggccattgg gggccttgga aaccagccat gtcctttggg ctctgtggag agctttagcc ttgcacggcg gcgctgggag gcattgcctg ccatgcccac tgcccgctgc tcctgctcta gtctgcaggc tgggccccgg ctgtttgtta ttgggggtgt ggcccagggc cccagtcaag ccgtggaggc actgtgtctg cgtgatgggg Protein function: Involved in pinching off the separated nuclei at the cleavage furrow and in cytokinesis (PubMed:20107318). Required for mitotic integrity and maintenance of chromosomal stability. Protects cells against mitotic errors, centrosomal amplification, micronucleus formation and aneuploidy. Plays a key role of midbody function involving abscission of the daughter cells during cytokinesis and appropriate chromosomal and nuclear segregation into the daughter cells (PubMed:22988245, PubMed:23713010). [The UniProt Consortium]