HECW2 (Vector pUC, Accession No. BC117194)

Length: 4719 Sequence: atggctagtt cagcccggga gcacctgctt tttgtgaggc gtcgaaatcc ccagatgcgg tacacattga gcccagagaa cctccagagc cttgccgccc agagctccat gccagagaac atgaccctgc agcgggccaa cagcgacacc gacctggtga cttctgagag ccgctccagc ttaactgcca gcatgtacga gtacacgctg gggcaagccc agaacctcat tatcttctgg gacattaaag aggaggtgga ccccagtgat tggattggac tttatcatat agatgagaat tctccagcca acttctggga ttctaagaac aggggtgtga ctggaacaca aaaagggcaa attgtatgga gaattgagcc tggaccctat ttcatggaac cggagataaa aatctgtttt aaatattacc acggcattag tggagccctg cgagccacga ccccctgcat caccgtgaag aacccagctg tgatgatggg ggcagaaggc atggagggag gtgcttcagg aaacctgcat tctcgaaaac ttgttagctt tacattgtca gatcttaggg cagttgggct aaagaaaggg atgttcttca atcctgaccc ttatcttaag atgtcaattc agccaggaaa gaagagcagt ttccccacct gtgcccacca cgggcaggag agacggtcta ctatcatcag taacaccacc aatccaattt ggcaccgaga gaaatattcc ttttttgcac ttcttactga tgtcttagaa attgaaatta aagacaaatt tgccaagagc cgtcccatca tcaagcgttt tctggggaaa ctaaccattc cagtccagag gctgctggag cgacaagcca tcggtgatca aatgctcagc tacaaccttg gcagaaggct cccagctgac cacgtgagtg ggtacctcca gtttaaagtg gaggttacgt cttctgttca tgaagatgcc tctccagaag ctgttggcac aatacttgga gtcaattctg tgaatggaga cttaggtagc ccttccgatg acgaggacat gccagggagc catcacgaca gccaggtgtg ctctaatggg ccagtttctg aggacagtgc tgccgatgga acccccaagc attcattcag gactagctcc actctggaaa tagacacaga ggaattaacc tctacgtctt caaggacctc acctcccaga ggacgtcagg attcactcaa tgattactta gatgctatcg aacacaatgg ccactccagg ccagggacag cgacctgctc tgagaggtcc atgggtgcct ctccgaaact gaggagtagt tttcccactg acacaagact caatgccatg cttcatattg attcagatga agaagatcac gagttccagc aagacctggg ttacccatct tccttggagg aggagggagg cctgatcatg tttagcaggg catccagagc tgatgatgga agcctgacat ctcagacaaa gctggaggac aaccctgttg agaatgagga agcctccaca cacgaagctg cttcctttga ggataagcca gaaaatcttc cagagcttgc agagagctcc ttacctgcag gcccagcccc agaggaaggt gaaggcggcc cagagcctca acccagtgct gaccagggca gtgctgaact gtgtggctct caagaggtag atcagcccac aagtggcgca gacacaggga cttccgatgc atcaggagga agccgaagag ccgtcagtga gaccgagtct ctcgatcagg gctctgagcc ttcccaggtg tcctctgaaa cagaacccag tgatcctgcc aggacagaga gtgtgagcga agccagcacc aggcctgagg gagagagtga cctggaatgc gctgacagct cctgcaatga gagtgtgacc acgcagctgt cctctgtgga cacacggtgc tcctctcttg agagcgcacg gtttcctgaa accccagcct tttcttctca ggaggaggaa gacggagcct gtgcagcaga gcccaccagc agtggccctg ccgaagggtc gcaggaatcc gtgtgcactg ctggttcttt acctgtggta caggtgccca gtggggagga tgaagggcca ggggcagaat cggccactgt acctgaccag gaggagctgg gggaggtctg gcagcggagg gggagcctgg agggagctgc agctgctgcc gagagcccac cgcaagaaga aggcagtgct ggggaggccc aaggcacctg tgaaggggca actgcccagg aggagggcgc tactggaggt tctcaagcca acggccacca gccactgcga tcactacctt cagtgcgcca ggatgttagc cggtaccaga gggtggacga ggctctccca ccaaactggg aggcacgcat tgacagccac ggcaggatct tctacgtgga tcacgtaaac agaaccacga cgtggcagcg accgacagct cccccagccc cgcaggtgct gcagagatct aactccatac agcaaatgga gcagctgaac cggcgatatc agagtatccg cagaaccatg accaatgaga ggcctgagga aaataccaat gctattgatg gggcagggga ggaagctgac tttcaccaag ccagtgcaga tttccgacgg gagaacatcc tgcctcactc tacctccaga tccaggatca cgttgctgtt acagtctccc cccgtgaagt tcctcatcag cccagagttc ttcaccgtgc tgcattctaa ccctagtgcc taccgcatgt ttacaaacaa cacgtgtttg aagcacatga tcaccaaagt ccggagggac acccaccact ttgaacgcta ccagcataac cgcgaccttg tgggattcct caacatgttc gcgaacaaac agctagagct gccgcgggga tgggaaatga aacatgatca ccagggcaag gcattctttg tggaccacaa ctcccgcacc accactttca ttgatccccg gctcccactt cagagcagta gacccacaag tgcgctggtt catcggcaac acctgacaag gcaacgcagc cacagtgcgg gtgaggtagg agaagattct cgacatgcag gaccaccagt tcttcccagg ccatccagta cattcaatac agtcagtagg ccacagtacc aggacatggt tccagtggct tacaatgaca agattgttgc atttctacgt caacccaata tctttgaaat tctacaggag cgtcaacctg atcttaccag gaatcactca ctcagggaga agatccaatt tatccgaact gaagggactc caggattggt gcgcctttca agcgatgcag accttgttat gttgctgagc ttatttgaag aagagataat gtcatatgtg cctccacatg ccttactcca ccccagctac tgtcagtccc cacgtggctc tcccgtgtca tctcctcaga actcgccagg tacccagcgt gccaatgccc gggctccagc cccttacaag cgggatttcg aagccaaact gaggaacttt tacaggaagt tagagactaa aggatatgga caaggcccag ggaagttaaa gttaattatc cgaagagatc acttactaga agatgctttt aatcagatta tgggctactc cagaaaagac ctgcagagaa ataagctata tgtcaccttc gttggggagg aagggctgga ttacagtggg ccttctagag agtttttctt cctggtatcc agagaactct ttaacccata ttatggctta tttgaatatt cagccaatga cacatacaca gtacaaataa gtcctatgtc tgcttttgta gacaatcacc atgaatggtt ccgattcagt ggtaggatcc ttggtcttgc actaatacac cagtatttgt tggatgcctt cttcacacgg cccttttata aggctcttct cagaattcta tgtgacctga gtgacctaga ataccttgat gaagagttcc atcagagcct gcagtggatg aaagacaatg atatccatga catcctagac ctcacgttca ctgtgaacga agaagtattt gggcagataa ctgaacgaga attaaagcca gggggtgcca atatcccagt tacagagaag aacaagaagg agtacatcga gaggatggtg aagtggagga ttgagagggg tgttgtacag caaacagaga gcttagtgcg tggcttctat gaggtggtgg atgccaggct ggtatctgtt tttgatgcaa gagaactgga attggtcatc gcaggcacag ctgaaataga cctaagtgat tggagaaaca acacagaata tagaggagga taccatgaca atcatattgt aattcggtgg ttctgggctg cagtggaaag attcaacaat gaacaacgac taaggttgtt acagtttgtt acaggcacat ccagcattcc ctatgaagga tttgcttcac tccgagggag taacggccca agaagattct gtgtggagaa atgggggaaa atcactgctc ttcccagagc gcatacatgt tttaaccgtc tggatctgcc tccctaccca tccttttcca tgctttatga aaaactgttg acagcagttg aagaaaccag tacttttgga Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73 (PubMed:12890487). Involved in the regulation of mitotic metaphase/anaphase transition (PubMed:24163370). [The UniProt Consortium]