GNPTG (Vector pUC, Accession No. BC014592)

Length: 915 Sequence: atggcggcgg ggctggcgcg gctcctgttg ctcctcgggc tctcggccgg cgggcccgcg ccggcaggtg cagcgaagat gaaggtggtg gaggagccca acgcgtttgg ggtgaacaac ccgttcttgc ctcaggccag tcgcctccag gccaagaggg atccttcacc cgtgtctgga cccgtgcatc tcttccgact ctcgggcaag tgcttcagcc tggtggagtc cacgtacaag tatgagttct gcccgttcca caacgtgacc cagcacgagc agaccttccg ctggaacgcc tacagtggga tcctcggcat ctggcacgag tgggagatcg ccaacaacac cttcacgggc atgtggatga gggacggtga cgcctgccgt tcccggagcc ggcagagcaa ggtggagctg gcgtgtggaa aaagcaaccg gctggcccat gtgtccgagc cgagcacctg cgtctacgcg ctgacgttcg agacccccct cgtctgccac ccccacgcct tgctagtgta cccaaccctg ccagaggccc tgcagcggca gtgggaccag gtagagcagg acctggccga tgagctgatc accccccagg gccatgagaa gttgctgagg acactttttg aggatgctgg ctacttaaag accccagaaa atgaacccac ccagctggag ggaggtcctg acagcttggg gtttgagacc ctggaaaact gcaggaaggc tcataaagaa ctctcaaagg agatcaaaag gctgaaaggt ttgctcaccc agcacggcat cccctacacg aggcccacag aaacttccaa cttggagcac ttgggccacg agacgcccag agccaagtct ccagagcagc tgcggggtga cccaggactg cgtgggagtt Protein function: Non-catalytic subunit of the N-acetylglucosamine-1- phosphotransferase complex, an enzyme that catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. Binds and presents the high mannose glycans of the acceptor to the catalytic alpha and beta subunits (GNPTAB). Enhances the rate of N-acetylglucosamine-1-phosphate transfer to the oligosaccharides of acid hydrolase acceptors. [The UniProt Consortium]