FBXO10 (Vector pUC, Accession No. BC125125)

Length: 2871 Sequence: ATGGAGGCTG GTGGCCTCCC CTTGGAGCTG TGGCGCATGA TCTTAGCCTA CTTGCACCTT CCCGACCTGG GCCGCTGCAG CCTGGTATGC AGGGCCTGGT ATGAACTGAT CCTCAGTCTC GACAGCACCC GCTGGCGGCA GCTGTGTCTG GGTTGCACCG AGTGCCGCCA TCCCAATTGG CCCAACCAGC CAGATGTGGA GCCTGAGTCT TGGAGAGAAG CCTTCAAGCA GCATTACCTT GCATCCAAGA CATGGACCAA GAATGCCTTG GACTTGGAGT CTTCCATCTG CTTTTCTCTA TTCCGCCGGA GGAGGGAACG ACGTACCCTG AGTGTTGGGC CAGGCCGTGA GTTTGACAGC CTGGGCAGTG CCTTGGCCAT GGCCAGCCTG TATGACCGAA TTGTGCTCTT CCCAGGTGTG TACGAAGAGC AAGGTGAAAT CATCTTGAAG GTGCCTGTGG AGATTGTAGG GCAGGGGAAG TTGGGTGAAG TGGCCCTGCT GGCCAGCATT GATCAGCACT GCTCAACCAC ACGCCTGTGC AACCTCGTCT TCACGCCAGC CTGGTTCTCA CCCATCATGT ATAAGACAAC ATCAGGTCAC GTCCAGTTTG ACAACTGCAA CTTTGAGAAC GGGCACATCC AGGTCCATGG CCCGGGTACT TGCCAAGTGA AGTTCTGTAC CTTCAAAAAC ACCCATATCT TCCTGCACAA CGTGCCCCTG TGTGTCCTGG AAAACTGTGA ATTTGTGGGC AGTGAAAACA ACTCTGTGAC TGTTGAGGGT CACCCATCTG CAGATAAGAA CTGGGCCTAC AAGTATCTAC TAGGGCTTAT CAAGTCCTCA CCCACTTTTC TCCCCACAGA GGACTCTGAC TTTTTAATGT CCCTGGACCT AGAGAGCCGG GACCAGGCCT GGAGCCCAAA GACCTGTGAC ATTGTTATCG AGGGCAGCCA GAGCCCTACC AGCCCAGCTT CTAGCTCCCC AAAGCCAGGC TCCAAGGCTG GCTCACAGGA GGCAGAGGTG GGTAGTGATG GTGAAAGGGT GGCCCAGACC CCGGACAGCA GCGATGGAGG CCTGAGTCCC AGCGGTGAGG ATGAAGATGA GGACCAGCTG ATGTACAGAC TATCCTACCA AGTGCAGGGC CCACGCCCTG TATTGGGGGG CTCATTTCTG GGCCCACCTC TACCAGGAGC ATCCATTCAG CTGCCCAGCT GCCTAGTGCT GAACTCACTG CAGCAGGAGC TGCAGAAGGA TAAGGAGGCC ATGGCACTGG CCAACTCCGT GCAGGGCTGC CTCATCCGCA AGTGCCTCTT CCGGGACGGG AAGGGAGGCG TCTTCGTCTG CTCCCACGGC AGAGCCAAGA TGGAAGGAAA CATCTTCCGG AACCTGACTT ACGCAGTGCG GTGTATACAT AATAGCAAGA TCATCATGCT CAGGAACGAC ATTTACCGCT GCCGAGCGTC AGGCATCTTT CTTCGCTTGG AGGGCGGTGG CTTGATTGCC GGCAACAACA TTTACCACAA TGCAGAGGCT GGTGTAGACA TCCGGAAAAA GTCCAACCCA CTCATACTGT GTAACCAGAT CCACCATGGC CTTCGCTCTG GCATTGTCGT CCTTGGCAAT GGGAAAGGCA TCATCCGGAA CAATCAAATC TTTTCCAATA AGGAGGCTGG CATTTACATC CTGTACCACG GAAACCCCGT TGTGAGCGGG AACCACATCT TCAAGGGCCG TGCTGCCGGC ATAGCAGTGA ATGAGAACGG CAAAGGCCTC ATCACAGAAA ATGTCATCCG TGAGAATCAG TGGGGAGGTG TGGACATCCG CCGTGGAGGG ATCCCCGTTC TCAGGAGTAA CCTCATCTGC TTTGGCTATT CAGATGGTGT GGTTGTGGGA GACGAAGGCA AAGGCCTCAT AGAAGGAAAT ACCATCTACG CTAACAAGGG CTGTGGTGTG TGGATGATGT CGTCCAGCCT CCCCCATGTC ACCAGCAATC ACGTCAGCTA CAATGGCCTG TATGGAGTGG CAGTATTTAG CCAGAAGGAT GGCTCCAGCG AGTTACCTCG AGGCCACAGG GCTCAAGAGA ACTTCAGCGA GGATGGGGAC GCCATCCTCT GGGAGACAGA GCTGGAGAAG GAGGACGACC CACTGCGCCG GCCCATCACC ATAGCTCTTG TTGAGTCTAA CAGTATTAAT CACAATGGAG CCTCAGGACT CTATGTCCAG AGCAGCGAGG CACTGCATGT CATCACCAAT GTGATCCACG CGAATGGGGA CAGAGGCATT ACTGTGGCCC AGAGCAGCCA ACCCACCCGA GTGGCCAACA ACAGCATCTC CTGCAACCGG CAAAGTGGGG TCAAGGTTGA GGCCCAGTGC AAAGTGGAGC TCCGGGGCAA TGGTATCTAT GACAACAGAG GCCACGGCAT TATCACCAAG GGCGACAGCA CCATCGTCAT TGAAAACGAT ATCATTGGCA ACCGGGGCAG CGGGCTGCAG CTGCTGCCCA GGTCCGACAC TAAAGTAATA AAGAACCGGA TCCACTCGTT CCGGGCCTAC GGCATCGCCG TGCGGGGCCG TGCCAAGGCC CTGGTGCAGG AAAACATCAT CTTCCAGGGC AAAACCAGTA AGACCATCTT TCAGCAGATC TCAAACAACC GAGAATGCAT CATGCAAAAC AACAAGTTCC TGGTCTTCAA GAAAAAGTCT GATACGTGGC GCCTGGTGAA CCCACCAGCA CGGCCCCACC TTGAAAATTC TCTCAGACGT CCCTCGGCAG CCCACAATGG GCAGAAGGTG ACAGCCATGG CAACGAGGAT CACAGCCCGG GTGGAAGGTG GTTACCACAG CAACCGCAGT GTCTTCTGCA CCATCCTGTG Protein function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. The SCF(FBXO10) complex mediates ubiquitination and degradation of BCL2, an antiapoptotic protein, thereby playing a role in apoptosis by controlling the stability of BCL2. [The UniProt Consortium]