DYNC1LI1 (Vector pUC, Accession No. BC131620)

Length: 1572 Sequence: ATGGCGGCCG TGGGGCGAGT CGGCTCCTTC GGTTCTTCTC CGCCGGGATT ATCCTCGACT TACACTGGCG GCCCCTTGGG CAACGAGATA GCGTCGGGCA ACGGTGGCGC CGCGGCAGGC GACGACGAGG ACGGGCAGAA CCTTTGGTCC TGCATCCTCA GCGAGGTCTC CACCCGCTCG CGCTCCAAGC TCCCTGCGGG GAAGAACGTG CTACTGCTGG GTGAAGATGG AGCTGGAAAA ACAAGCTTAA TAAGAAAAAT TCAGGGAATA GAGGAGTATA AGAAAGGAAG AGGATTGGAA TATTTGTACT TAAATGTGCA TGATGAAGAC AGGGATGATC AAACAAGATG TAATGTTTGG ATCTTAGATG GAGACCTATA TCACAAAGGC CTCCTTAAAT TTTCACTGGA TGCCGTATCT CTGAAGGATA CTCTAGTTAT GCTGGTTGTT GACATGTCAA AGCCTTGGAC TGCTTTGGAT TCTTTACAGA AATGGGCAAG TGTTGTTAGA GAACATGTTG ACAAACTGAA AATCCCTCCT GAAGAAATGA AACAAATGGA ACAAAAGTTG ATTAGAGACT TCCAAGAATA TGTAGAGCCA GGAGAAGACT TCCCGGCTTC TCCCCAGAGA AGAAATACTG CGTCACAAGA AGACAAAGAT GACAGTGTAG TTTTACCTCT GGGTGCGGAT ACACTTACAC ATAACTTGGG CATTCCAGTA CTAGTAGTTT GCACAAAGTG TGATGCCATT AGTGTATTGG AGAAAGAACA TGACTACAGA GATGAACATT TTGATTTTAT TCAGTCACAT ATCCGGAAGT TTTGTTTACA GTATGGTGCA GCACTTATTT ACACTTCAGT AAAAGAAAAC AAAAATATAG ACTTAGTATA TAAATACATC GTTCAGAAAC TATATGGATT TCCCTATAAG ATTCCTGCTG TTGTTGTGGA AAAGGATGCA GTATTTATTC CAGCAGGGTG GGATAATGAT AAGAAAATAG GAATATTACA TGAAAATTTT CAAACATTAA AAGCAGAAGA TAATTTTGAA GACATCATAA CTAAACCACC TGTTCGAAAG TTTGTACATG AGAAGGAAAT TATGGCAGAA GATGATCAGG TGTTTCTTAT GAAGCTACAG TCCCTTTTAG CAAAGCAACC ACCAACTGCA GCTGGAAGGC CTGTGGATGC CTCACCAAGA GTCCCAGGAG GCTCCCCACG AACACCAAAT AGATCTGTAT CATCTAATGT TGCCAGCGTG TCACCCATTC CTGCTGGGTC AAAAAAAATT GATCCAAACA TGAAAGCTGG AGCTACAAGT GAAGGCGTTC TGGCAAATTT CTTCAACAGT TTGTTGAGTA AAAAGACTGG CTCTCCAGGA GGCCCTGGTG TGAGTGGTGG TAGCCCTGCA GGTGGGGCTG GAGGTGGAAG CAGTGGTTTA CCACCATCCA CCAAAAAGTC AGGCCAGAAG CCTGTCTTAG ATGTTCATGC AGAACTAGAC AGAATTACAC GAAAACCAGT TACAGTTTCT CCCACAACAC CTACATCTCC TACGGAAGGA GAAGCTTCTT Protein function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress through the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores. [The UniProt Consortium]