COPG2 (Vector pUC, Accession No. BC017443)

Length: 2400 Sequence: atgacgcgat tgtttcaatc taatgatcaa acattgagga gaatgtgcta ccttaccatc aaagaaatgg ctaccatctc tgaggatgtg ataattgtca caagcagtct gactaaagac atgactggaa aagaagatgt ataccgaggc ccggccatca gagctctctg caggatcacc gatggaacaa tgttgcaagc cattgaaaga tacatgaagc aggccattgt ggataaagtt tccagtgtat ccagttcagc actggtatct tccctgcaca tgatgaagat aagctatgat gtggttaagc gctggatcaa tgaagcccaa gaagctgcat caagtgataa tattatggtc cagtaccatg cattgggagt cctgtatcac cttagaaaga atgatcgact tgctgtttcc aagatgttga ataagtttac taaatctggt ctcaagtcac agtttgctta ctgcatgctg atccgaattg ccagtcgctt actaaaagaa actgaggatg gccatgaaag tccactgttt gatttcattg agagctgctt gcgaaataaa catgaaatgg ttatttatga agctgcttca gctatcatcc atcttcctaa ctgcactgca agagagttgg cacctgctgt ttcagttctt caacttttct gtagttctcc taagccagcc ttgagatatg cagctgtgag gaccttgaac aaggtggcaa tgaagcaccc ctctgctgtt actgcctgca atctggactt agaaaactta atcacagact caaacagaag cattgctacc ttagccatta ctacactcct caaaacagga agtgagagca gtgtggaccg gctcatgaag cagatatctt cttttgtgtc tgaaatctca gatgagttca aggtggtggt tgtacaggca attagtgctc tctgtcagaa ataccctcga aagcacagtg tcatgatgac tttcctctcc aacatgctcc gagatgatgg aggctttgag tacaagcggg ccattgtgga ctgtataatc agcattgtgg aagagaaccc tgagagtaaa gaagcaggcc tagcccacct ttgtgaattc attgaggact gtgaacacac tgttctggct actaagattc tacacttgtt gggcaaagag ggccctagaa cgcctgtccc ctccaaatat atccgtttta tttttaatag ggttgtcctg gagaatgagg ctgtcagagc tgctgctgtg agtgctttgg ctaaatttgg ggctcagaat gagagtcttc tcccaagcat ccttgtactc ttacagaggt gtatgatgga tactgatgac gaggtacgag acagagctac cttctatctg aatgtgctgc agcagaggca gatggcacta aatgccacat atatctttaa tggtttgacg gtctctgtac cagggatgga aaaagcctta caccagtaca cgttggagcc ttcagaaaaa ccgtttgaca tgaaatcaat tcctcttgct atggctcctg tctttgaaca gaaagcagaa atcacacttg tggctactaa gccagagaag ttggctcctt ccaggcaaga cattttccaa gaacaattgg ctgccattcc tgagtttctg aatataggac ccttgttcaa gtcttctgag cctgttcaac ttacagaagc agagacagaa tattttgttc gatgtatcaa gcacatgttt accaatcaca tcgtgttcca gtttgactgc accaacactc tcaatgacca gctgctggaa aaagtgacag tgcagatgga gccatcagat tcctatgaag tgctgtcttg tatcccagcc cccagccttc cttataacca accaggaata tgttacactc ttgttcgttt gcctgatgat gaccctacag cagttgcagg ctcctttagc tgcaccatga agtttacagt ccgggactgt gaccctaaca ctggagttcc agatgaggat gggtatgatg atgagtatgt gctggaagat ctcgaagtga ctgtgtctga ccatattcag aaagtactga agcctaactt tgctgctgct tgggaagagg tgggagatac ctttgagaaa gaggaaacct ttgccctcag ttctaccaaa acccttgaag aggctgtcaa caatatcatc acatttctgg gcatgcagcc atgtgagagg tccgataaag tacctgagaa caagaattcc cattcgctct atctggcagg tatattcaga ggtggctatg atttattggt gaggtccagg ctggccttag ccgatggagt gaccatgcag gtgactgtca gaagtaaaga gagaacacct gtagatgtta tcttagcttc Protein function: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. [The UniProt Consortium]