ASXL2 (Vector pUC, Accession No. BC042999)

Length: 2757 Sequence: atgaaaagaa ctaaatgtgc tgacattgac gttgagacac cggactccat tctggttaat acaaatctgc gagcactgat caacaagcac acattttcag tccttcctgg agattgccag caacgactgc ttttactact cccagaggta gatcgacagg ttggtccaga tggtttaatg aagttaaatg gctcagccct taacaatgaa ttcttcactt cagcagccca aggctggaag gaaagactct cagaaggtga gtttacacct gagatgcagg tgagaattcg acaagagatt gagaaggaga aaaaagtgga gccatggaaa gaacaattct ttgaaagcta ctatgggcag agttctggcc tgagccttga agattctaag aaattgacag cttctcccag tgatcccaaa gtaaagaaaa ccccagctga acaaccaaaa tccatgcctg tgtcagaggc ctctcttatc agaatagttc cagtagtctc ccagtcagag tgtaaagaag aagcattgca aatgtcatca ccaggcagaa aagaagagtg tgaaagccaa ggtgaagtgc agccgaactt ctccacatct tcagagcccc tgctttcctc agctctcaat acacatgagc ttagcagcat tcttcccatc aagtgcccaa aggatgagga tctcttggag cagaagccag tcacctctgc tgaacaggaa tctgagaaga accatctcac cacagcttct aattataaca aaagtgaaag ccaagaatct ttagttacat cgccaagcaa acccaagagt cctggggttg aaaaaccaat agtgaagccc acagcaggag cgggtccaca ggagactaat atgaaagaac ctctagcaac tcttgttgat cagagcccag aaagcctcaa gaggaagtct tccctcaccc aagaagaggc ccctgtgagc tgggagaaga ggccacgtgt cactgagaat cgccagcacc agcagccatt tcaggtctca ccacagccct ttctcaatag aggggacaga atccaggtgc gaaaagtacc acctctcaag atcccggtct ccagaatctc ccccatgccg tttcatccat cgcaggtctc tcccagggct cgttttccag tctccatcac tagtcctaac agaacaggag ccagaactct tgcagacatc aaagcaaaag cccaactggt caaagcacag agggcagcag ctgccgctgc cgccgcagct gctgcagccg cctcagttgg agggaccatt ccaggacctg gcccaggggg tggacaaggt ccaggagagg gtggtgaagg gcagactgct agaggaggca gtccaggctc agacagagtc agtgaaactg gaaagggccc cacactggaa ctggcaggaa ctggaagcag gggaggtacg agagagcttt taccctgtgg tccagagact cagccccagt ctgagaccaa gaccacccca agccaggcac agcctcatag tgtctctgga gcacaactac agcaaacccc cccagtgcct ccaacacctg ccgtcagtgg agcatgcaca agtgtcccat caccagtcca catagagaaa ttggataatg aaaaactgaa ccccaccaga gcaacagcca cagtggcctc tgtcagccat ccacaagggc ccagtagttg cagacaggag aaagcacctt ctccaacagg tttccagctg gaagacatct ccacaagcca gaggttcatg ctgggttttg ctggcagaag gacatccaaa cctgcaatgg cagggcacta cttactgaat atttctacct acggccgggg ctcagagagc tttaggagga cccattctgt aaaccctgaa gatcgttttt gtctaagcag ccccactgaa gccttgaaaa tgggatatac agactgtaaa aatgcaacag gagagagtag cagcagcaaa gaagatgaca ctgatgagga aagtactggt gatgagcagg aatctgtcac agtgaaagag gagccccagg tttcccagag tgctggcaag ggtgacacaa gttcaggacc tcacagcagg gaaactctat ctaccagtga ttgcttagct agcaagaatg tgaaggctga gataccattg aatgagcaaa ccactttaag taaggagaat tacctgttca ctagaggcca aacatttgat gaaaagaccc tagccagaga tttaattcag gcagcacaga agcagatggc tcatgcagtg agaggtaagg caatccgtag cagccccgag cttttcagtt ctactgttct tcctctgcct gcagacagcc ccacccacca gcccctactc cttccacccc tgcaaacccc gaagttgtat ggaagcccca cccagatagg gccaagctat agaggcatga tcaatgtctc cacctcatct gacatggacc ataactctgc tgtaccaggt agccaggtat ctagcaatgt aggtgatgtc atgtcatttt cagtgactgt cactaccatc cctgctagcc aagctatgaa tcccagcagc catggccaga ccattcctgt tcaggcgttc tccgaagaga acagcataga gggcacgcct tcgaaatgtt actgccgctt gaaagccatg atcatgtgca aaggctgtgg cgctttctgc catgatgatt gcatcggccc ctccaaactg tgcgtctcct gccttgtcgt Protein function: Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation- inducing activity, the function seems to involve differential recruitment of acetylated and methylated histone H3. [The UniProt Consortium]