ARHGAP29 (Vector pENTR223.1, Accession No. BC022483)

Length: 1182 Sequence: atgattgctc acaaacagaa aaagacaaag aaaaaacgtg cttgggcatc aggtcaactc tctactgata ttacaacttc tgaaatgggg ctcaagtcct taagttccaa ctctattttt gatccggatt acatcaagga gttggtgaat gatatcagga agttctccca catgttacta tatttgaaag aagccatatt ttcagactgt tttaaagaag ttattcatat acgtctagag gaactgctcc gtgttttaaa gtctataatg aataaacatc agaacctcaa ttctgttgat cttcaaaatg ctgcagaaat gctcactgca aaagtgaaag ctgtgaactt cacagaagtt aatgaagaaa acaaaaacga tctcttccag gaagtgtttt cttctattga aactttggca tttacctttg gaaatatcct tacaaacttc cttatgggag atgtaggcaa tgattcatta ttgcgactgc ctgtttctcg agaaactaag tcgtttgaaa atgtttctgt ggaatcagtg gactcatcca gtgaaaaagg aaatttttcc cctttagaac tagacaacgt gctgttaaag aacactgact ctatcgagct ggctttgtca tatgctaaaa cttggtcaaa atatactaag aacatagttt catgggttga aaaaaagctt aacttggaat tggagtccac tagaaatatg gtcaagttgg cagaggcaac tagaactaac attggaattc aggagttcat gccactgcag tctctgttta ctaatgctct tcttaatgat atagaaagca gtcacctttt acaacaaaca attgcagctc tccaggctaa caaatttgtg cagcctctac ttggaaggaa aaatgaaatg gaaaaacaaa ggaaagaaat aaaagagctt tggaaacagg agcaaaataa aatgcttgaa gcagagaatg ctctcaaaaa ggcaaaatta ttatgcatgc aacgtcaaga tgaatatgag aaagcaaagt cttccatgtt tcgtgcagaa gaggagcatc tgtcttcaag tggcggatta gcaaaaaatc tcaacaagca actagaaaaa aagcgaaggt tggaagagga ggctctccaa aaagtaacga tctttttctt ttttatttgc aagttgaatt Protein function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis. [The UniProt Consortium]