AP3B1 (Vector pUC, Accession No. BC038444)

Length: 3285 Sequence: atgtccagca atagttttcc ttacaatgag cagtccggag gaggggaggc gacggagctg ggtcaggagg cgacctcaac catttccccc tcgggggcct tcggcctctt tagcagcgat ttgaagaaga atgaagatct aaagcaaatg ttagagagca acaaagattc tgctaaactg gatgctatga agcggattgt tgggatgatt gcaaaaggga aaaatgcatc tgaactgttt cctgctgttg tgaagaatgt ggccagtaaa aatattgaga tcaagaagtt ggtatatgtt tacctggttc gatatgctga agaacagcag gatcttgcac tcctgtccat aagcactttt cagcgagctc tgaaggaccc aaaccaacta attcgtgcaa gcgctttgag agttctgtca agtattagag tgccaattat tgtacctatc atgatgcttg ctattaagga agcttctgct gacttatcac catatgttag gaagaatgca gcccatgcaa tacaaaaatt atacagcctt gatccagagc agaaggaaat gttaattgaa gtaattgaaa aacttctgaa agataaaagc acattggtag ctggcagtgt tgtgatggct tttgaagaag tatgcccgga cagaatagat ctgattcata aaaattaccg caagctatgt aacttactag tggatgttga agagtggggg caggttgtca taatccacat gctaactcga tatgctcgga cacagtttgt cagcccttgg aaagagggtg atgaattaga agacaatgga aagaatttct acgaatctga tgatgatcag aaggaaaaga ctgacaaaaa gaagaagccg tatactatgg atccagatca tagactctta attagaaata caaagccttt gcttcagagc aggaatgctg cggtggttat ggcagttgct cagctgtatt ggcacatatc accaaaatct gaagctggca taatttctaa atcactagtg cgtttacttc gtagcaatag ggaggtgcag tatattgtcc tacaaaatat agcaactatg tcaattcaaa gaaaggggat gtttgaacct tatctgaaga gtttctatgt taggtcaact gatccaacta tgatcaagac actgaagctt gaaattttga caaacttggc aaatgaagcc aacatatcaa ctcttcttcg agaatttcag acctatgtga aaagccagga taaacaattt gcagcagcca ctattcagac tataggcaga tgtgcaacca acatcttgga agtcactgac acgtgcctca atggcttggt ctgtctgctg tccaacaggg atgaaatagt tgttgctgaa agtgtggttg ttataaagaa attactgcaa atgcaacctg cacaacatgg tgaaattatt aaacatatgg ccaaactcct ggacagtatc actgttcctg ttgctagagc aagtattctt tggctaattg gagaaaactg tgaacgagtt cctaaaattg cccctgatgt tttgaggaag atggctaaaa gcttcactag tgaagatgat ctggtaaaac tgcagatatt aaatctggga gcaaaattgt atttaaccaa ctccaaacag acaaaattgc ttacccagta catattaaat ctcggcaagt atgatcaaaa ctacgacatc agagaccgta caagatttat taggcagctt attgttccga atgaaaagag tggagcttta agtaaatatg ccaaaaaaat attcctagca caaaagcctg caccactgct tgagtctcct tttaaagata gagatcattt ccagcttggc accttatctc atactctcaa cattaaagct actgggtacc tggaattatc taattggcca gaggtggcgc ccgacccatc agttcgaaat gtagaagtaa tagagttggc aaaagaatgg accccagcag gaaaagcaaa gcaagagaat tctgctaaga agttttattc tgaatctgag gaagaggagg actcttctga tagtagcagt gacagtgaga gtgaatctgg aagtgaaagt ggagaacaag gcgaaagtgg ggaggaagga gacagcaatg aggacagcag tgaggactcc tccagtgagc aggacagtga gagtggacgg gagtcaggcc tagaaaacaa aagaacagcc aagaggaact caaaagccaa aggaaaaagt gattctgaag atggggagaa ggaaaatgaa aaatctaaaa cttcagattc ttcaaatgac gaatctagtt caatagaaga cagttcttcc gattctgaat cagagtcaga acctgaaagt gaatctgaat ccagaagagt cactaaggag aaagaaaaga aaacaaagca agatagaact cctcttacca aagatgtttc acttctagat ctggatgatt ttaacccagt atccactcca gttgcacttc ccacaccagc tctttctcca agtttgatgg ctgatcttga aggtttacac ttgtcaactt cctcttcagt catcagtgtc agtactcctg catttgtacc aacgaaaact cacgtgctgc ttcatcgaat gagtggaaaa ggactagctg cccattattt ctttccaaga cagccttgca tttttggtga taagatggtc tctatacaaa taacactgaa taacactact gatcgaaaga tagaaaatat ccacataggg gaaaaaaaac ttcctatagg catgaaaatg catgttttta atccaataga ctctcttgag cctgagggat ccattacagt ttcaatgggt attgactttt gtgattctac tcagactgcc agtttccagt tgtgtaccaa ggatgattgc ttcaatgtta atattcagcc acctgttgga gaactgcttt tacctgtggc catgtcagag aaagatttta agaaagagca aggagtgcta acaggaatga atgaaacttc tgctgtaatc attgctgcac cacagaattt cactccctct gtgatctttc agaaggttgt aaatgtagcc aatgtaggtg cagtcccttc tggccaggat aatatacaca ggtttgcagc taaaactgtg cacagtgggt cattgatgct agtcacagtg gaactgaagg aaggctctac agcccagctt atcataaaca ctgagaaaac tgtgattggc tctgttctgc tgcgggaact gaagcctgtc ctgtctcagg Protein function: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. [The UniProt Consortium]