ACOT2 (Vector pUC, Accession No. BC004436)

Length: 1266 Sequence: atggcggcga cgctgatcct ggagcctgcg ggccgctgct gctgggacga accggtgcga atcgccgtgc gcggcctagc cccggagcag ccggtcacgc tgcgcgcgtc cctgcgcgac gagaagggcg cgcttttcca ggcccacgcg cgctaccgcg ccgacactct tggcgagctg gacctggagc gcgcgcccgc gctgggcggc agcttcgcgg ggcttgagcc catggggctg ctctgggcct tggagcccga gaaacctttg gtgcggctgg tgaagcgcga cgtgcgaacg cccttggccg tggagctgga ggtgctggat ggccacgacc ccgaccccgg gcggctgctg tgccagacgc ggcacgagcg ctacttcctc ccgcccgggg tgcggcgcga gccggtgcgc gtgggccggg tgcgaggcac gctcttcctg ccgccagaac ctgggccctt tcctgggatt gtggacatgt tcggaactgg aggtggcctg ctggagtatc gggctagtct gctggctggg aagggttttg ctgtgatggc tctggcttat tataactatg aagacctccc caagaccatg gagacgctcc atctggagta ctttgaagaa gccatgaact acttgctcag tcatcccgag gtaaaaggtc caggagttgg gctgcttgga atttccaaag ggggtgagct ctgcctttcc atggcctctt tcctgaaggg catcacggct gctgtcgtca tcaacggctc tgtggccaat gttgggggaa ccttacgcta caagggcgag accctgcccc ctgtgggcgt caacagaaat cgcatcaagg tgaccaaaga tggctatgca gacattgtgg atgtcctgaa cagccctttg gaaggacctg accagaagag cttcattcct gtggaaaggg cagagagcac cttcctgttc ctggtaggtc aggatgacca caactggaag agtgagttct atgctaatga ggcctgtaaa cgcttgcagg cccatgggag gagaaagccc cagatcatct gttacccaga gacagggcac tatattgagc ctccttactt ccccctgtgt cgggcttccc tgcatgcctt ggtgggcagt cctattatct ggggagggga gcccagggct catgccatgg ctcaggtgga tgcttggaaa caactccaga ctttcttcca caaacacttg ggtggccgcg aggggacaat cccatcaaaa Protein function: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed:16940157). Acyl-coenzyme A thioesterase 2/ACOT2 displays higher activity toward long chain acyl CoAs (C14-C20) (PubMed:16940157, PubMed:10944470). The enzyme is involved in enhancing the hepatic fatty acid oxidation in mitochondria. [The UniProt Consortium]