tetranor-PGEM

tetranor-Prostaglandin E metabolite (tetranor-PGEM) is the major urinary metabolite of PGE2 (Cay-14010). Urine levels of tetranor-PGEM are increased in patients with diabetic nephropathy. Increased urine levels are also associated with a higher risk of breast cancer in postmenopausal women with a body mass index (BMI) of less than 25 kg/m2.Formal Name: 9,15-dioxo-11alpha-hydroxy-13,14-dihydro-2,3,4,5-tetranor-prostan-1,20-dioic acid. CAS Number: 24769-56-0. Synonyms: tetranor-Prostaglandin E Metabolite. Molecular Formula: C16H24O7. Formula Weight: 328.4. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: Not Stable, PBS (pH 7.2): 1 mg/ml. SMILES: O[C@H]1[C@H](CCC(CCCCC(O)=O)=O)[C@@H](CCC(O)=O)C(C1)=O. InChi Code: InChI=1S/C16H24O7/c17-10(3-1-2-4-15(20)21)5-6-11-12(7-8-16(22)23)14(19)9-13(11)18/h11-13,18H,1-9H2,(H,20,21)(H,22,23)/t11-,12-,13-/m1/s1. InChi Key: ZJAZCYLYLVCSNH-JHJVBQTASA-N.