Syringaldehyde

Syringaldehyde is a polyphenol that has been found in E. granulatus and has diverse biological activities. It inhibits LPS-induced COX-2 activity in RAW 264.7 cells with an IC50 value of 19.23 µM. Syringaldehyde inhibits the proliferation of HCT116, Caco-2, and HT-29 colon cancer cells (IC50s = 56.3, 35.9, and 68.6 µM, respectively). It decreases plasma glucose levels in a rat model of diabetes induced by streptozotocin (STZ, Cay-13104) when administered at doses ranging from 1.8 to 7.2 mg/kg. Syringaldehyde (25 and 50 mg/kg) reduces infarct size in a rat model of myocardial infarction induced by isoproterenol (Cay-15592).Formal Name: 4-hydroxy-3,5-dimethoxy-benzaldehyde. CAS Number: 134-96-3. Synonyms: NSC 41153, SM 707, VND 3207. Molecular Formula: C9H10O4. Formula Weight: 182.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:7): 0.12 mg/ml, Ethanol: 1 mg/ml. lambdamax: 216, 231, 310 nm. SMILES: O=CC1=CC(OC)=C(C(OC)=C1)O. InChi Code: InChI=1S/C9H10O4/c1-12-7-3-6(5-10)4-8(13-2)9(7)11/h3-5,11H,1-2H3. InChi Key: KCDXJAYRVLXPFO-UHFFFAOYSA-N. Origin: Synthetic.