(S)-KT109

(S)-KT109 is the (S) isomer of the diacylglycerol lipase beta (DAGLbeta) inhibitor KT109 (Cay-18933). (S)-KT109 is a less potent inhibitor of DAGLbeta (IC50 = 39.81 nM), DAGLalpha-mediated hydrolysis of 1-stearoyl-2-arachidonoyl-sn-glycerol (IC50 = 794.3 nM), and alpha/beta-hydrolase domain-containing protein 6 (ABHD6, IC50 = 630.9 nM) than (R)-KT109 (Cay-25682).Formal Name: (4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[(2S)-2-(phenylmethyl)-1-piperidinyl]-methanone. CAS Number: 2055172-61-5. Molecular Formula: C27H26N4O. Formula Weight: 422.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/mL, DMSO: 10 mg/mL. lambdamax: 279 nm. SMILES: O=C(N1N=NC(C2=CC=C(C3=CC=CC=C3)C=C2)=C1)N4[C@H](CC5=CC=CC=C5)CCCC4. InChi Code: InChI=1S/C27H26N4O/c32-27(30-18-8-7-13-25(30)19-21-9-3-1-4-10-21)31-20-26(28-29-31)24-16-14-23(15-17-24)22-11-5-2-6-12-22/h1-6,9-12,14-17,20,25H,7-8,13,18-19H2/t25-/m0/s1. InChi Key: JKJMWHULJIOKPJ-VWLOTQADSA-N.