Rosuvastatin EP Impurity A (calcium salt)

Rosuvastatin EP impurity A is a potential impurity in commercial preparations of the HMG-CoA reductase inhibitor rosuvastatin.Formal Name: 7-[4-(4-fluorophenyl)-2-[[(2-hydroxy-2-methylpropyl)sulfonyl]methylamino]-6-(1-methylethyl)-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid, hemicalcium salt. CAS Number: 1714147-47-3. Molecular Formula: C25H33FN3O7S . 1/2Ca. Formula Weight: 558.7. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble, Methanol: Soluble. SMILES: O=S(N(C)C1=NC(C(C)C)=C(C(C2=CC=C(C=C2)F)=N1)/C=C/[C@@H](O)C[C@@H](O)CC([O-])=O)(CC(C)(C)O)=O.O=S(N(C)C3=NC(C(C)C)=C(C(C4=CC=C(C=C4)F)=N3)/C=C/[C@@H](O)C[C@@H](O)CC([O-])=O)(CC(C)(C)O)=O.[Ca+2]. InChi Code: InChI=1S/2C25H34FN3O7S.Ca/c2*1-15(2)22-20(11-10-18(30)12-19(31)13-21(32)33)23(16-6-8-17(26)9-7-16)28-24(27-22)29(5)37(35,36)14-25(3,4)34,/h2*6-11,15,18-19,30-31,34H,12-14H2,1-5H3,(H,32,33),/q,,+2/p-2/b2*11-10+,/t2*18-,19-,/m11./s1. InChi Key: SMYOVFJEKJPZQC-YFPLZLEBSA-L.