PEG(2000)-DSPE

PEG(2000)-DSPE is a PEGylated form of 1,2-distearoyl-sn-glycero-3-PE (DSPE, Cay-15095). It has been used in the generation of micelles and in combination with other lipids in the formation of liposomes. Liposomes containing PEG(2000)-DSPE and encapsulating the DNA topoisomerase inhibitor doxorubicin (Cay-15007) and the flavonoid quercetin (Cay-10005169) reduce tumor growth in an MCF-7/adr multidrug-resistant breast cancer mouse xenograft model.Formal Name: (R)-2,3-bis(stearoyloxy)propyl (138-oxo-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98,101,104,107,110,113,116,119,122,125,128,131,134,137-hexatetracontaoxa-139-azahentetracontahectan-141-yl) phosphate, monosodium salt. Synonyms: PEG(2000)-1,2-DSPE, PEG2000-DSPE, Polyethylene Glycol-2000-1,2-Distearoyl-sn-glycero-3-PE, Polyethylene Glycol-2000-1,2-Distearoyl-sn-glycero-3-Phosphoethanolamine, Polyethylene Glycol-2000-1,2-Distearoyl-sn-glycero-3-Phosphatidylethanolamine. Molecular Formula: C133H263NO55P . Na. Formula Weight: 2810.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: Slightly soluble, Water: Slightly soluble. SMILES: COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC(NCCOP(OC[C@H](OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)([O-])=O)=O.[Na+]. InChi Code: InChI=1S/C221H440NO99P.Na/c1-5-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-218(223)317-214-217(321-219(224)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-6-2)215-320-322(226,227)319-39-38-222-221(225)318-216-220(315-212-210-313-208-206-311-204-202-309-200-198-307-196-194-305-192-190-303-188-186-301-184-182-299-180-178-297-176-174-295-172-170-293-168-166-291-164-162-289-160-158-287-156-154-285-152-150-283-148-146-281-144-142-279-140-138-277-136-134-275-132-130-273-128-126-271-123-122-269-119-118-267-115-114-265-111-110-263-107-106-261-103-102-259-99-98-257-95-94-255-91-90-253-87-86-251-83-82-249-79-78-247-75-74-245-71-70-243-67-66-241-63-62-239-59-58-237-55-54-235-51-50-233-47-46-231-43-42-229-7-3)316-213-211-314-209-207-312-205-203-310-201-199-308-197-195-306-193-191-304-189-187-302-185-183-300-181-179-298-177-175-296-173-171-294-169-167-292-165-163-290-161-159-288-157-155-286-153-151-284-149-147-282-145-143-280-141-139-278-137-135-276-133-131-274-129-127-272-125-124-270-121-120-268-117-116-266-113-112-264-109-108-262-105-104-260-101-100-258-97-96-256-93-92-254-89-88-252-85-84-250-81-80-248-77-76-246-73-72-244-69-68-242-65-64-240-61-60-238-57-56-236-53-52-234-49-48-232-45-44-230-41-40-228-4,/h217,220H,5-216H2,1-4H3,(H,222,225)(H,226,227),/q,+1/p-1/t217-,220?,/m1./s1. InChi Key: MDBBDFMSMPHWGY-VJEKXSTHSA-M.