PAMAM Dendrimer G5.5 Carboxylate (sodium salt) (water solution)

PAMAM dendrimer G5.5 carboxylate (PAMAM G5.5 carboxylate) is a polyamidoamine (PAMAM) dendrimer with carboxylate termini that has been used as a drug delivery system in vitro. It is approximately 103.9 Å in diameter in water and has 192 surface groups. Unlike PAMAM dendrimer G3.0 amine (Cay-39073), PAMAM G5.5 carboxylate (100 µg/ml) does not induce cytotoxicity or autophagy in A549 cells. Bimetallic nanoparticles of PAMAM G5.5 carboxylate with gold and platinum scavenge DPPH (Cay-14805) radicals in a cell-free assay. Complexes of PAMAM G5.5 carboxylate with the active component of cisplatin are cytotoxic to A2780 ovarian cancer cells (IC50 = 1.48 µM).CAS Number: 202009-67-4. Synonyms: PAMAM G5.5 Carboxylate, Polyamidoamine Dendrimer G5.5 Carboxylate. Molecular Formula: [NH2(CH2)2NH2]:(G=5.5),dendri PAMAM(NHCH2CH2COONa)256. Formula Weight: 52900.2. Formulation: (Request formulation change), A solution in water. Solubility: Water: soluble.