oxy-Arachidonoyl Ethanolamide

AEA acts as an endogenous mimic of Delta9-THC, the psychotropic component of marijuana. oxy-AEA is the O-alkyl-N-acyl oxyhomologue of AEA. oxy-AEA is selective for the peripheral cannabinoid (CB2) receptor with Ki values of 0.47 and 0.081 µM for hCB1 and hCB2, respectively. In comparison, AEA has a greater affinity for the central cannabinoid (CB1) receptor with Ki values of 0.07 and 0.18 µM for hCB1 and hCB2, respectively. oxy-AEA is the first known fatty acid amide with a reversed CB1/CB2 affinity ratio.Formal Name: N-(2-hydroxyethoxy)-5Z,8Z,11Z,14Z-eicosatetraenamide. CAS Number: 883296-70-6. Synonyms: oxy-AEA, oxy-Anandamide. Molecular Formula: C22H37NO3. Formula Weight: 363.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 1 mg/ml, DMSO: 1 mg/ml, Ethanol: 25 mg/ml, Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml. SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NOCCO. InChi Code: InChI=1S/C22H37NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-26-21-20-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-,16-15-. InChi Key: ANMKTCMIIFBOGG-DOFZRALJSA-N.