OH-C-Chol

OH-C-Chol is a cationic cholesterol derivative. OH-C-Chol, as a component of lipoplexes with DOPE (Cay-15091), has been used for siRNA delivery and gene silencing in MCF-7 cells as well as in mice via intravenous injection, resulting in lipoplex accumulation in the liver.Formal Name: (3beta)-cholest-5-en-3-ol 3-[N-[2-[(2-hydroxyethyl)amino]ethyl]carbamate]. CAS Number: 496801-51-5. Molecular Formula: C32H56N2O3. Formula Weight: 516.8. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/mL, Ethanol: 10 mg/mL, Ethanol:PBS (pH 7.2) (1:6): 0.14 mg/mL. SMILES: C[C@H](CCCC(C)C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(NCCNCCO)=O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C. InChi Code: InChI=1S/C32H56N2O3/c1-22(2)7-6-8-23(3)27-11-12-28-26-10-9-24-21-25(37-30(36)34-18-17-33-19-20-35)13-15-31(24,4)29(26)14-16-32(27,28)5/h9,22-23,25-29,33,35H,6-8,10-21H2,1-5H3,(H,34,36)/t23-,25+,26+,27-,28+,29+,31+,32-/m1/s1. InChi Key: IVKGTZVIOSLOAM-PTHRTHQKSA-N.