Lyso-globotetraosylceramide (d18:1)

Lyso-globotetraosylceramide is a form of globotetraosylceramide (Gb4) lacking the fatty acyl group. It binds to the Shiga-like toxin pig verotoxin of edema disease (VTE) in a glycolipid binding assay. Lyso-globotetraosylceramide is acylated to stearic acid (Cay-10011298) via a condensation reaction mediated by sphingolipid ceramide N-deacylase to form a ceramide. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1541]Formal Name: N-((2S,3R,4R,5R,6R)-2-(((2R,3R,4S,5S,6R)-2-(((2R,3R,4R,5R,6S)-6-(((2R,3S,4R,5R,6R)-6-(((2S,3R,E)-2-amino-3-hydroxyoctadec-4-en-1-yl)oxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide. Synonyms: lyso-Globoside. Molecular Formula: C44H80N2O22. Formula Weight: 989.1. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Chloroform:Methanol:Water (2:1:0.1): soluble. SMILES: O[C@@H]1[C@H]([C@@H](O[C@H](CO)[C@@H]1O)O[C@@H]2[C@H]([C@H](O[C@H](CO)[C@@H]2O)O[C@H]3[C@H](O[C@H]([C@H](O)[C@H]3O)O[C@@H]4[C@H](O[C@H]([C@H](O)[C@H]4O)OC[C@@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)N)CO)CO)O)NC(C)=O. InChi Code: InChI=1S/C44H80N2O22/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-24(52)23(45)21-61-42-35(58)33(56)38(27(19-49)64-42)66-43-36(59)34(57)39(28(20-50)65-43)67-44-37(60)40(31(54)26(18-48)63-44)68-41-29(46-22(2)51)32(55)30(53)25(17-47)62-41/h15-16,23-44,47-50,52-60H,3-14,17-21,45H2,1-2H3,(H,46,51)/b16-15+/t23-,24+,25+,26+,27+,28+,29+,30-,31-,32+,33+,34+,35+,36+,37+,38+,39-,40-,41-,42+,43-,44+/m0/s1. InChi Key: GKLWBWQLQGVPSV-JGPNDWKISA-N.