Luteolin 7-O-Rutinoside

Luteolin 7-O-rutinoside is a polyketide-derived flavonoid glycoside that has been found in V. bugulifolium and has diverse biological activities. It scavenges DPPH (Cay-14805) radicals in a cell-free assay when used at concentrations ranging from 1 to 50 µM. Luteolin 7-O-rutinoside is active against B. subtilis, S. aureus, A. tumefaciens, M. luteus, E. coli, and P. aeruginosa (MICs = 100-200 µg/ml). It is also active against C. albicans, S. cerevisiae, and C. lusitaniae (MICs = 100, 200, and 50 µg/ml, respectively). Luteolin 7-O-rutinoside (57.6 µg/animal) decreases hepatic and renal injury and increases survival in a mouse model of polyphosphate-induced lethal endotoxemia.Formal Name: 7-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5-hydroxy-4H-1-benzopyran-4-one. CAS Number: 20633-84-5. Synonyms: Luteolin 7-Rutinoside, Luteolin 7-beta-Rutinoside, Scolymoside, Skolimoside. Molecular Formula: C27H30O15. Formula Weight: 594.5. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. SMILES: O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O)C=C2OC(C5=CC(O)=C(C=C5)O)=C1. InChi Code: InChI=1S/C27H30O15/c1-9-20(32)22(34)24(36)26(39-9)38-8-18-21(33)23(35)25(37)27(42-18)40-11-5-14(30)19-15(31)7-16(41-17(19)6-11)10-2-3-12(28)13(29)4-10/h2-7,9,18,20-30,32-37H,8H2,1H3/t9-,18+,20-,21+,22+,23-,24+,25+,26+,27+/m0/s1. InChi Key: MGYBYJXAXUBTQF-FOBVWLSUSA-N. Origin: Synthetic.