Lipid PPz-2R1

NEU

Artikelnummer	Größe	Manual	Lieferzeit	Preis
Cay43160-5	5 mg	-	6 - 10 Werktage*	109,00 €
Cay43160-10	10 mg	-	6 - 10 Werktage*	206,00 €
Cay43160-25	25 mg	-	6 - 10 Werktage*	488,00 €

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Lipid PPz-2R1 is an ionizable cationic lipid that has been used in the generation of lipid... mehr

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Produktinformationen "Lipid PPz-2R1"

Lipid PPz-2R1 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. LNPs containing lipid PPz-2R1 and encapsulating an mRNA reporter selectively accumulate in lungs over the heart, liver, spleen, and kidneys in mice. LNPs containing lipid PPz-2R1 and encapsulating mRNA encoding phosphatase and tensin homolog (PTEN) increase PTEN protein levels in PTEN-deficient Lewis lung carcinoma (LLC) cells. Lipid PPz-2R1-containing LNPs encapsulating PTEN mRNA reduce tumor growth in an orthotopic murine LLC model when administered alone or in combination with an antibody targeting programmed cell death protein 1 (PD-1).. Solulibility: Ethanol: Soluble: =10 mg/ml: .

Schlagworte:	piperazine-1,4-diylbis(hexane-6,1-diyl) bis(2-hexyldecanoate)
Hersteller:	Cayman Chemical
Hersteller-Nr:	43160

Eigenschaften

Anwendung:	Ionizable cationic lipidoid, LNP formation
MW:	763.29 D
Formel:	C48H94N2O4
Reinheit:	>98%
Format:	Solution

Datenbank Information

CAS :

2832061-40-0| Passende Produkte

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	+20°C (International: -20°C)
Signalwort:	Danger
GHS-Piktogramme:
H-Sätze:	H225, H319, H333
P-Sätze:	P210, P233, P240, P241, P242, P243, P264, P280, P303+361+353, P304+312, P305+351+338, P337+313, P370+378, P403+235, P501