Lipid DIM1

Lipid DIM1 is an ionizable cationic lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for mRNA delivery in vitro. LNPs containing lipid DIM1 and encapsulating mRNA encoding a luciferase reporter induce luminescence in primary mouse adipose stem cells (ASCs).Formal Name: 1,1',1'',1'''-(((((3R,3aS,6S,6aS)-hexahydrofuro[3,2-b]furan-3,6-diyl)bis(oxy))bis(propane-3,1-diyl))bis(azanetriyl))tetrakis(dodecan-2-ol). CAS Number: 2820155-36-8. Molecular Formula: C60H120N2O8. Formula Weight: 997.6. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Chloroform: Sparingly soluble: 1-10 mg/ml, Ethanol: Soluble: >10 mg/ml, Methanol: Slightly soluble: 0.1-1 mg/ml. SMILES: OC(CCCCCCCCCC)CN(CC(O)CCCCCCCCCC)CCCO[C@H]1[C@@](OC2)([H])[C@](OC1)([H])[C@H]2OCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC. InChi Code: InChI=1S/C60H120N2O8/c1-5-9-13-17-21-25-29-33-39-53(63)47-61(48-54(64)40-34-30-26-22-18-14-10-6-2)43-37-45-67-57-51-69-60-58(52-70-59(57)60)68-46-38-44-62(49-55(65)41-35-31-27-23-19-15-11-7-3)50-56(66)42-36-32-28-24-20-16-12-8-4/h53-60,63-66H,5-52H2,1-4H3/t53?,54?,55?,56?,57-,58+,59-,60-/m0/s1. InChi Key: YTDBTDJNDXVDHF-WZLTYCDFSA-N.