Hyodeoxycholic Acid MaxSpec(R) Standard

Hyodeoxycholic acid (HDCA) is a secondary bile acid. It is produced from lithocholic acid (Cay-20253) by gut bacteria. Dietary administration of HDCA (1.25% w/w) decreases plasma VLDL and LDL cholesterol levels and reduces fasting glucose levels and atherosclerotic lesion size in LDL receptor knockout mice fed a Western diet. Serum levels of HDCA are increased in patients with Crohn's disease or ulcerative colitis. Hyodeoxycholic acid MaxSpec(R) standard is a quantitative grade standard of Hyodeoxycholic Acid (Cay-20294) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This hyodeoxycholic acid MaxSpec(R) standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.Formal Name: (3alpha,5beta,6alpha)-3,6-dihydroxy-cholan-24-oic acid. CAS Number: 83-49-8. Synonyms: alpha-Hyodeoxycholic Acid, HDCA, NSC 60672. Molecular Formula: C24H40O4. Formula Weight: 392.6. Purity: >95%. Formulation: (Request formulation change), A solution in methanol at 100 µg/ml. SMILES: C[C@H](CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])C[C@H](O)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C. InChi Code: InChI=1S/C24H40O4/c1-14(4-7-22(27)28)17-5-6-18-16-13-21(26)20-12-15(25)8-10-24(20,3)19(16)9-11-23(17,18)2/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16+,17-,18+,19+,20+,21+,23-,24-/m1/s1. InChi Key: DGABKXLVXPYZII-SIBKNCMHSA-N.