Glycolithocholic Acid

Glycolithocholic acid is a glycine-conjugated form of the secondary bile acid lithocholic acid (Cay-20253). It is increased in the liver of mice fed a diet supplemented with ursodeoxycholic acid (Cay-15121). Glycolithocholic acid levels are decreased in the plasma following subcutaneous administration of PEG-obestatin(Cys10, Cys13), a modified peptide hormone, in lean or diet-induced obese mice. Serum glycolithocholic acid levels increase with age in children.Formal Name: N-[(3alpha,5beta)-3-hydroxy-24-oxocholan-24-yl]-glycine. CAS Number: 474-74-8. Synonyms: Lithocholylglycine. Molecular Formula: C26H43NO4. Formula Weight: 433.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml, DMSO: 20 mg/ml, Ethanol: 20 mg/ml. SMILES: C[C@H](CCC(NCC(O)=O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C. InChi Code: InChI=1S/C26H43NO4/c1-16(4-9-23(29)27-15-24(30)31)20-7-8-21-19-6-5-17-14-18(28)10-12-25(17,2)22(19)11-13-26(20,21)3/h16-22,28H,4-15H2,1-3H3,(H,27,29)(H,30,31)/t16-,17-,18-,19+,20-,21+,22+,25+,26-/m1/s1. InChi Key: XBSQTYHEGZTYJE-OETIFKLTSA-N.