Epimedin C

Epimedin C is a flavonoid glycoside that has been found in E. koreanum and has diverse biological activities. It scavenges DPPH (Cay-14805) radicals in a cell-free assay (IC50 = 142 µM). Epimedin B increases proliferation of UMR-106 osteoblasts by 30.4 and 41.6% when used at concentrations of 0.1 and 10 µM, respectively. It inhibits ear edema induced by phorbol 12-myristate 13-acetate (TPA, Cay-10008014) in mice (ED50 = 192 nmol/ear).Formal Name: 3-[[6-deoxy-2-O-(6-deoxy-alpha-L-mannopyranosyl)-alpha-L-mannopyranosyl]oxy]-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one. CAS Number: 110642-44-9. Synonyms: Baohuoside VI. Molecular Formula: C39H50O19. Formula Weight: 822.8. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, PBS (pH 7.2): 1 mg/ml. lambdamax: 272 nm. SMILES: C/C(C)=C\CC1=C2C(C(C(O[C@H]3[C@@H]([C@@H]([C@H]([C@@H](O3)C)O)O)O[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O)=C(C5=CC=C(C=C5)OC)O2)=O)=C(C=C1O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)CO)O. InChi Code: InChI=1S/C39H50O19/c1-14(2)6-11-19-21(54-38-32(50)29(47)26(44)22(13-40)55-38)12-20(41)23-27(45)35(33(56-34(19)23)17-7-9-18(51-5)10-8-17)57-39-36(30(48)25(43)16(4)53-39)58-37-31(49)28(46)24(42)15(3)52-37/h6-10,12,15-16,22,24-26,28-32,36-44,46-50H,11,13H2,1-5H3/t15-,16-,22+,24-,25-,26+,28+,29-,30+,31+,32+,36+,37-,38+,39-/m0/s1. InChi Key: ULZLIYVOYYQJRO-JIYCBSMMSA-N. Origin: Plant/Epimedii folium.