Elaidic Acid

Elaidic acid is a monounsaturated trans fatty acid and the 9-trans isomer of oleic acid (Cay-90260, Cay-24659) that has been found in partially hydrogenated cooking oils. It reduces HHT and HETE formation and increases synthesis of prostaglandin E2 (PGE2, Cay-14010), PGF2alpha (Cay-16010, Cay-16020), PGD2 (Cay-12010), and thromboxane B2 (TXB2, Cay-19030) induced by arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) in isolated human platelets. Elaidic acid (0.1-5 mmol/L) induces apoptosis in human umbilical vein endothelial cells (HUVECs). In vivo, elaidic acid (100 mg/kg) reduces cardiac and hepatic autophagy induced by palmitic acid (Cay-10006627) in mice.Formal Name: 9E-octadecenoic acid. CAS Number: 112-79-8. Synonyms: C18:1(9E), FA 18:1, 9(E)-Oleic Acid, trans-Oleic Acid. Molecular Formula: C18H34O2. Formula Weight: 282.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: 0.15 M Tris-HCl pH 8.5: 1 mg/ml, DMF: 100 mg/ml, DMSO: 100 mg/ml, Ethanol: 100 mg/ml. SMILES: CCCCCCCC/C=C/CCCCCCCC(=O)O. InChi Code: InChI=1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9+. InChi Key: ZQPPMHVWECSIRJ-MDZDMXLPSA-N. Side Chain Carbon Sum: 18:1.