Eicosapentaenoic Acid-d5 ethyl ester

Eicosapentaenoic acid-d5 ethyl ester is intended for use as an internal standard for the quantification of eicosapentaenoic acid ethyl ester (Cay-10008884) by GC- or LC-MS. Eicosapentaenoic acid (EPA) ethyl ester is an esterified form of the omega-3 fatty acid EPA (Cay-90110, Cay-90110.1, Cay-21908). Dietary administration of EPA ethyl ester (41.4 g/100 g of total dietary fatty acids) increases the ex vivo activity of hepatic beta-oxidation enzymes. It also reduces total hepatic triglyceride levels and increases the omega-3 fatty acid content of hepatic triglycerides and phospholipids, as well as increases the total levels of omega-3 fatty acids in rats. EPA ethyl ester (1 g/kg) reverses increases in plasma cholesterol levels and reduces circulating triglyceride levels in rats fed a high-fat diet. Formulations containing eicosapentaenoic acid ethyl ester have been used as adjuncts in the treatment of hypertriglyceridemia.Formal Name: 5Z,8Z,11Z,14Z,17Z-eicosapentaenoic-19,19,20,20,20-d5 acid, ethyl ester. CAS Number: 2483831-19-0. Synonyms: EPA-d5 ethyl ester, SFE 22:5-d5. Molecular Formula: C22H29D5O2. Formula Weight: 335.5. Purity: >99% deuterated forms (d1-d5). Formulation: (Request formulation change), A solution in ethanol. Solubility: Ethanol: 1 mg/ml. SMILES: [2H]C([2H])([2H])C([2H])([2H])/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(OCC)=O. InChi Code: InChI=1S/C22H34O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24-4-2/h5-6,8-9,11-12,14-15,17-18H,3-4,7,10,13,16,19-21H2,1-2H3/b6-5-,9-8-,12-11-,15-14-,18-17-/i1D3,3D2. InChi Key: SSQPWTVBQMWLSZ-IHLFCWNDSA-N.