Dihomo-gamma-Linolenic Acid-d6

Dihomo-gamma-Linolenic Acid-d6 (DGLA-d6) is intended for use as an internal standard for the quantification of DGLA (Cay-90230) by GC- or LC-MS. DGLA (20:3), an elongation product of gamma-linolenic acid (18:3), is rapidly metabolized by fatty acid desaturases to produce arachidonic acid (20:4). DGLA is metabolized through the cyclooxygenase pathway to produce 1-series prostaglandins, (PGs), including PGE1. In mice, DGLA supplementation in the diet can reduce atopic dermatitis and atherosclerosis.Formal Name: 8Z,11Z,14Z-eicosatrienoic-8,9,11,12,14,15-d6 acid. CAS Number: 81540-86-5. Synonyms: DGLA-d6, FA 20:3-d6. Molecular Formula: C20H28D6O2. Formula Weight: 312.5. Purity: >99% deuterated forms (d1-d6). Formulation: (Request formulation change), A solution in methyl acetate. Solubility: 0.15 M Tris-HCl pH 8.5: 1 mg/ml, DMF: 100 mg/ml, DMSO: 100 mg/ml, Ethanol: 100 mg/ml, PBS (pH 7.2): 100 µg/ml. SMILES: [2H]/C(CCCCCCC(O)=O)=C([2H])/C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCCC. InChi Code: InChI=1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13H,2-5,8,11,14-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-/i6D,7D,9D,10D,12D,13D. InChi Key: HOBAELRKJCKHQD-JALKMEHMSA-N. Side Chain Carbon Sum: 20:3.