Dihomo-gamma-Linolenic Acid

Dihomo-gamma-Linolenic Acid (DGLA, 20:3), an elongation product of gamma-linolenic acid (18:3), is rapidly metabolized by fatty acid desaturases to produce arachidonic acid (20:4). DGLA is metabolized through the cyclooxygenase pathway to produce 1-series prostaglandins, including PGE1. In mice, DGLA supplementation in the diet can reduce atopic dermatitis and atherosclerosis.Formal Name: 8Z,11Z,14Z-eicosatrienoic acid. CAS Number: 1783-84-2. Synonyms: DGLA, cis-8,11,14-Eicosatrienoic Acid, FA 20:3, gamma-Homolinolenic Acid. Molecular Formula: C20H34O2. Formula Weight: 306.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: 0.15 M Tris-HCl pH 8.5: >1 mg/ml (from Oleic Acid), DMF: >100 mg/ml (from Oleic Acid), DMSO: >100 mg/ml (from Oleic Acid), Ethanol: >100 mg/ml (from Oleic Acid), PBS pH 7.2: <100 µg/ml (from Oleic Acid). SMILES: CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O. InChi Code: InChI=1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13H,2-5,8,11,14-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-. InChi Key: HOBAELRKJCKHQD-QNEBEIHSSA-N. Side Chain Carbon Sum: 20:3.