Cholestyramine

Cholestyramine is a bile acid sequestrant. It binds to bile acids in the intestine and inhibits their absorption, which increases the synthesis of bile acids from cholesterol in the liver, thereby lowering serum LDL levels. Cholestyramine reduces serum cholesterol levels and increases bile acid excretion in the feces without changing the bile acid pool size in rabbits. Formulations containing cholestyramine have been used as adjuncts in the treatment of primary hypercholesterolemia.CAS Number: 11041-12-6. Formulation: (Request formulation change), A solid. SMILES: C[N+](C)(C)CC(C=C1)=CC=C1C(CC)CC(C2=CC=CC=C2)CC.CCC(C)C.[Cl-].