C16 Sphingomyelin-13C (d18:1/16:0-13C)

C16 Sphingomyelin-13C (d18:1/16:0-13C) is intended for use as an internal standard for the quantification of C16sphingomyelin (Cay-10007946) by GC- or LC-MS. C16 Sphingomyelin is a naturally occurring sphingolipid. Levels of C16 sphingomyelin are elevated in the prefrontal cortex and cerebellum in a rat model of diabetes induced by streptozotocin (STZ, Cay-13104), as well as in the liver in mouse models of Niemann-Pick type C1 disease. Plasma levels of C16 sphingomyelin are decreased in patients with prostate cancer. Model membranes containing C16 sphingomyelin, 1-palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC, Cay-15102), and cholesterol (Cay-9003100) have been used in the study of lipid raft dynamics and membrane organization. [Matreya, LLC. Catalog No. 2200]Formal Name: [R-[R*,S*-(E)]]-4-hydroxy-7-(1-hydroxy-2-hexadecenyl)-N,N,N-trimethyl-9-oxo-3,5-dioxa-8-aza-4-phosphatetracosan-1-aminium-9-13C, 4-oxide, inner salt. CAS Number: 144236-99-7. Synonyms: Palmitoyl Sphingomyelin-13C, N-Palmitoyl-D-erythro-Sphingosylphosphorylcholine-13C, SM(d18:1/16:0-13C), Sphingomyelin (d18:1/16:0-13C). Molecular Formula: C38[13C]H79N2O6P. Formula Weight: 704.0. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Chloroform: soluble, Ethanol: soluble, Methanol: soluble. SMILES: O=[13C](CCCCCCCCCCCCCCC)N[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)[C@H](O)/C=C/CCCCCCCCCCCCC. InChi Code: InChI=1S/C39H79N2O6P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-38(42)37(36-47-48(44,45)46-35-34-41(3,4)5)40-39(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h30,32,37-38,42H,6-29,31,33-36H2,1-5H3,(H-,40,43,44,45)/b32-30+/t37-,38+/m0/s1/i39+1. InChi Key: RWKUXQNLWDTSLO-UHDUVUCGSA-N.