C16 alpha-Glucosylceramide (d18:1/16:0) (synthetic)

C16 alpha-Glucosylceramide is a bioactive glycosphingolipid. It is a precursor in the synthesis of C16 lactosylceramide (Cay-24352) that is formed via metabolism of C16 ceramide (Cay-10681) by glucosylceramide synthase. Inhalation of C16 glucosylceramide reduces lung colonization by P. aeruginosa and increases survival in a mouse model of cystic fibrosis. C16 Glucosylceramide levels are elevated in the plasma of Parkinson's disease patients with cognitive impairments. This product is fully synthetic and has no variations in the fatty acyl chain or sphingoid backbone.Formal Name: N-[(1S,2R,3E)-1-[(beta-D-glucopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-hexadecanamide. CAS Number: 74365-77-8. Synonyms: N-omega-CD3-Hexadecanoyl-glucopsychosine, GluCer(d18:1/16:0). Molecular Formula: C40H77NO8. Formula Weight: 700.0. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: :, Methanol: Sparingly soluble: 1-10 mg/ml. SMILES: O[C@H]1[C@H](O)[C@@H](CO)O[C@H](OC[C@H](NC(CCCCCCCCCCCCCCC)=O)[C@H](O)/C=C/CCCCCCCCCCCCC)[C@@H]1O. InChi Code: InChI=1S/C40H77NO8/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(43)33(32-48-40-39(47)38(46)37(45)35(31-42)49-40)41-36(44)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,33-35,37-40,42-43,45-47H,3-26,28,30-32H2,1-2H3,(H,41,44)/b29-27+/t33-,34+,35+,37+,38-,39+,40-/m0/s1. InChi Key: VJLLLMIZEJJZTE-PPCZGQGBSA-N.