beta-Sitosterol-D-glucoside

beta-Sitosterol-D-glucoside is a sterol glycoside that has been found in P. pseudotaimingasa and has diverse biological activities. It is active against E. coli and S. aureus. beta-Sitosterol-D-glucoside inhibits alpha-amylase and alpha-glucosidase and scavenges DPPH (Cay-14805) radicals (IC50s = 46.4, 17, and 155 µM, respectively). It inhibits the proliferation of HepG2 and SMMC-7721 hepatocellular carcinoma cells (IC50s = 143.4 and 138.73 µg/ml, respectively) and migration and invasion in the same cells when used at concentrations of 50 or 100 µg/ml. beta-Sitosterol-D-glucoside (200 µl of a 200 µg/ml solution) increases survival and decreases the number of kidney colony-forming units (CFUs) in a mouse model of candidiasis induced by C. albicans.Formal Name: (3beta)-stigmast-5-en-3-yl beta-D-glucopyranoside. CAS Number: 474-58-8. Synonyms: BSSG, Daucosterol, NSC 165962, Stigma-5-en-3-O-beta-glucoside. Molecular Formula: C35H60O6. Formula Weight: 576.9. Purity: >90%. Formulation: (Request formulation change), A solid. Solubility: Methanol: Soluble. SMILES: C[C@@]1([C@@]2([H])[C@H](C)CC[C@@H](CC)C(C)C)[C@](CC2)([H])[C@@](CC=C3[C@@]4(CC[C@H](O[C@]([C@@H]([C@@H](O)[C@@H]5O)O)([H])O[C@@H]5CO)C3)C)([H])[C@]4([H])CC1. InChi Code: InChI=1S/C35H60O6/c1-7-22(20(2)3)9-8-21(4)26-12-13-27-25-11-10-23-18-24(14-16-34(23,5)28(25)15-17-35(26,27)6)40-33-32(39)31(38)30(37)29(19-36)41-33/h10,20-22,24-33,36-39H,7-9,11-19H2,1-6H3/t21-,22-,24+,25+,26-,27+,28+,29-,30-,31+,32-,33-,34+,35-/m1/s. InChi Key: NPJICTMALKLTFW-OFUAXYCQSA-N. Origin: Plant/Dioscorea nipponica Makino.