Asaraldehyde

Asaraldehyde is a plant metabolite that has been found in D. carota and has diverse biological activities. It selectively inhibits COX-2 over COX-1 when used at a concentration of 100 µg/ml and inhibits aggregation of washed isolated rabbit platelet-rich plasma induced by arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) or collagen (IC50s = 53.7 and 27.6 µM, respectively). Asaraldehyde (1 mg/disc) is active against C. perfringens and C. difficile. It decreases triglyceride, perilipin 1, and leptin levels and increases glycerol and hormone-sensitive lipase (HSL) levels in differentiated 3T3-L1 mouse adipocytes, as well as enhances osteogenesis induced by osteogenic differentiation medium in primary human periodontal ligament stem cells when used at a concentration of 100 µg/ml. Asaraldehyde has been used as a building block in the synthesis of various chalcones and flavonoids with anticancer and antioxidant activities.Formal Name: 2,4,5-trimethoxy-benzaldehyde. CAS Number: 4460-86-0. Synonyms: Asaronaldehyde, Asarylaldehyde, NSC 89299, 2,4,5-Trimethoxybenzaldehyde. Molecular Formula: C10H12O4. Formula Weight: 196.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 25 mg/ml, DMSO: 30 mg/ml, Ethanol: 10 mg/ml. lambdamax: 236, 275, 342 nm. SMILES: O=CC1=CC(OC)=C(C=C1OC)OC. InChi Code: InChI=1S/C10H12O4/c1-12-8-5-10(14-3)9(13-2)4-7(8)6-11/h4-6H,1-3H3. InChi Key: IAJBQAYHSQIQRE-UHFFFAOYSA-N. Origin: Synthetic.