Arachidonoyl-L-carnitine (chloride)

Carnitine facilitates the transport of fatty acids into the mitochondria to be used in fatty acid metabolism. It does so by accepting acyl groups from fatty acids complexed with coenzyme A, which yields esterified carnitine or acylcarnitines that enable the transport of fatty acyl groups into the inner mitochondrial matrix. beta-Oxidation of fatty acids in mitochondria is inhibited by uncoupling conditions, thus changes in circulating levels of various acylcarnitines have been used to identify alterations in metabolic state. Arachidonoyl-L-carnitine formed from carnitine conjugated to arachidonic acid (Cay-90010).Formal Name: (R)-3-carboxy-2-((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyloxy)-N,N,N-trimethylpropan-1-aminium, monochloride. CAS Number: 2133455-98-6. Synonyms: CAR 20:4, C20:4 Carnitine, L-Arachidonoylcarnitine, L-Carnitine arachidonoyl ester. Molecular Formula: C27H46NO4 . Cl. Formula Weight: 484.1. Purity: >95%. Formulation: (Request formulation change), A solution in chloroform. Solubility: DMF: 20 mg/ml, DMSO: 10 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O[C@H](CC(O)=O)C[N+](C)(C)C)=O.[Cl-]. InChi Code: InChI=1S/C27H45NO4.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-27(31)32-25(23-26(29)30)24-28(2,3)4,/h9-10,12-13,15-16,18-19,25H,5-8,11,14,17,20-24H2,1-4H3,1H/b10-9-,13-12-,16-15-,19-18-,/t25-,/m1./s1. InChi Key: RMLLFLPIJLXQGA-NWALNVDBSA-N. Side Chain Carbon Sum: 20:4.